⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19039335 | 0.76 | — | — | |
| SCHEMBL9779253 | 0.74 | — | — | |
| SCHEMBL113911 | 0.72 | — | — | |
| SCHEMBL17382261 | 0.72 | — | — | |
| SCHEMBL20689264 | 0.72 | — | — | |
| SCHEMBL1357520 | 0.72 | — | — | |
| SCHEMBL1778986 | 0.70 | L3MBTL1 (0.40) | — | |
| SCHEMBL21468598 | 0.70 | NPSR1 (0.35) | — | |
| SCHEMBL1459898 | 0.69 | KDM4E (0.38) | — | |
| SCHEMBL21720382 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 287 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116874425-A | Method for rapidly preparing 4-bromo-3- (bromomethyl) -1-methyl-1H-pyrazole based on microchannel continuous flow technology | 都创(上海)医药开发有限公司 | 2023-10-13 | — | — | CN | claimed |
| CN-111233768-B | Preparation method of 3- (difluoromethyl) -1-methyl-1H-pyrazole-4-carboxylic acid ethyl ester | 徐州圣元化工有限公司 | 2021-08-03 | — | — | CN | claimed |
| US-20250313575-A1 | MACROCYCLES AS LRRK2 INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | MERCK SHARP & DOHME LLC (US) | 2025-10-09 | — | — | US | disclosed |
| US-20250257076-A1 | SUBSTITUTED PYRROLIDINE-2-CARBOXYLIC ACID DERIVATIVES AS cGAS INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2025-08-14 | — | — | US | disclosed |
| CN-119698414-A | Indole-phenyl piperidine compound and preparation method and application thereof | 深圳信立泰药业股份有限公司 | 2025-03-25 | — | — | CN | disclosed |
| EP-4482832-A1 | 5-[7-(3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBONYL)-1,2,3,4 TETRAHYDROISOQUINOLIN-6-Y L]-1H-PYRROLE-3-CARBOXAMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS PRO-APOPTOTIC AGENTS | Les Laboratoires Servier (FR) | 2025-01-01 | — | — | EP | disclosed |
| CN-119053587-A | 5- [7- (3, 4-Dihydro-1H-isoquinoline-2-carbonyl) -1,2,3,4 tetrahydroisoquinolin-6-yl ] -1H-pyrrole-3-carboxamide derivatives, pharmaceutical compositions containing same and use thereof as pro-apoptotic agents | 法国施维雅药厂 | 2024-11-29 | — | — | CN | disclosed |
| US-20240360165-A1 | INHIBITORS OF CYCLIN DEPENDENT KINASE 7 (CDK7) | MEDIC LIFE SCIENCES, INC. | 2024-10-31 | — | — | US | disclosed |
| CN-118852154-A | Carboxamide substituted hetero tricyclic derivative, preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2024-10-29 | — | — | CN | disclosed |
| WO-2023224894-A9 | MACROCYCLES AS LRRK2 INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | MERCK SHARP & DOHME LLC (US) | 2024-10-17 | — | — | WO | disclosed |
| US-20240245699-A1 | PYRROLE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SERVIER LAB (FR) | 2024-07-25 | — | — | US | disclosed |
| US-20070182895-A1 | Liquid crystal display device | FUJI PHOTO FILM CO., LTD. (JP) | 2007-08-09 | — | — | US | disclosed |
| US-20070134446-A1 | Retardation film, method for producing the same, polarizing plate and liquid crystal display | KONICA MINOLTA OPTO, INC. | 2007-06-14 | — | — | US | disclosed |
| US-20070134446-A1 | Retardation film, method for producing the same, polarizing plate and liquid crystal display | KONICA MINOLTA OPTO, INC. | 2007-06-14 | — | — | US | disclosed |
| US-20070097302-A1 | RETARDATION FILM, POLARIZING PLATE AND VERTICAL ALIGNMENT MODE LIQUID CRYSTAL DISPLAY | KONICA MINOLTA OPTO, INC. (JP) | 2007-05-03 | — | — | US | disclosed |
| US-20070097302-A1 | RETARDATION FILM, POLARIZING PLATE AND VERTICAL ALIGNMENT MODE LIQUID CRYSTAL DISPLAY | KONICA MINOLTA OPTO, INC. (JP) | 2007-05-03 | — | — | US | disclosed |
| US-20070019133-A1 | Polarizing plate and liquid crystal display device | KONICA MINOLTA OPTO, INC. (JP) | 2007-01-25 | — | — | US | disclosed |
| US-20070019133-A1 | Polarizing plate and liquid crystal display device | KONICA MINOLTA OPTO, INC. (JP) | 2007-01-25 | — | — | US | disclosed |
| US-7166339-B1 | Phase contrast plate comprising one sheet of cellulose ester film containing aromatic compound | FUJIFILM CORPORATION (JP) | 2007-01-23 | — | — | US | disclosed |
| US-7166339-B1 | Phase contrast plate comprising one sheet of cellulose ester film containing aromatic compound | FUJIFILM CORPORATION (JP) | 2007-01-23 | — | — | US | disclosed |