Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF2R | P11717 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | GJB2 | P29033 | 5/20 | 0.48 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.45 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.45 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.45 |
| ▸ | GBA1 | P04062 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TLR4 | O00206 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8864499 | 0.93 | IGF2R (0.56) | IGF2RMAPK1GJB2LGALS8LGALS3 | |
| SCHEMBL8864321 | 0.93 | IGF2R (0.56) | IGF2RMAPK1GJB2LGALS8LGALS3 | |
| SCHEMBL5145571 | 0.93 | IGF2R (0.56) | IGF2RMAPK1GJB2LGALS8LGALS3 | |
| SCHEMBL8686568 | 0.92 | IGF2R (0.55) | IGF2RMAPK1GJB2LGALS8LGALS3 | |
| SCHEMBL8691787 | 0.92 | IGF2R (0.55) | IGF2RMAPK1GJB2LGALS8LGALS3 | |
| SCHEMBL8687950 | 0.92 | IGF2R (0.55) | IGF2RMAPK1GJB2LGALS8LGALS3 | |
| SCHEMBL28155326 | 0.86 | GJB2 (0.50) | IGF2RMAPK1GJB2GBA1TLR4 | |
| SCHEMBL20684592 | 0.84 | MAPK1 (0.60) | IGF2RMAPK1GJB2LGALS8LGALS3 | |
| SCHEMBL23016771 | 0.84 | MAPK1 (0.65) | IGF2RMAPK1GJB2LGALS8LGALS3 | |
| SCHEMBL21067398 | 0.84 | MAPK1 (0.65) | IGF2RMAPK1GJB2LGALS8LGALS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012024688-A1 | MULTIPHASE SYSTEMS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2012-02-23 | — | — | WO | disclosed |