SCHEMBL6720724

SCHEMBL6720724

C[C@@H]1C[C@H](O)CC(C)(C)C1=O

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ENO1 P06733 1/20 0.32
PTPN1 P18031 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5713354 1.00 ENO1 (0.32) ENO1PTPN1
SCHEMBL8378487 1.00 ENO1 (0.32) ENO1PTPN1
SCHEMBL8382270 1.00 ENO1 (0.32) ENO1PTPN1
SCHEMBL8165368 1.00 ENO1 (0.32) ENO1PTPN1
SCHEMBL7838483 1.00 ENO1 (0.32) ENO1PTPN1
SCHEMBL960112 1.00 ENO1 (0.32) ENO1PTPN1
SCHEMBL8677887 1.00 ENO1 (0.32) ENO1PTPN1
SCHEMBL21862868 0.77
SCHEMBL2689523 0.76
SCHEMBL28473651 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0775685-B1 Process for the isolation of trans- and cis-4-hydroxy-2,2,6-trimethylcyclohexan-1-one from mixtures of these isomers BASF AG (DE) 1999-04-07 EP claimed
US-5777173-A Preparation of pure trans- and cis-4-Hydroxy-2,2,6-trimethylcyclohexan-1-one from isomerc mixtures BASF AKTIENGESELLSCHAFT (DE) 1998-07-07 US claimed
EP-0775685-A1 Process for the isolation of trans- and cis-4-hydroxy-2,2,6-trimethylcyclohexan-1-one from mixtures of these isomers BASF AKTIENGESELLSCHAFT (DE) 1997-05-28 EP claimed
EP-0520391-B1 Chemical modification method of a diastereomer and separation method thereof KANEGAFUCHI CHEMICAL IND (JP) 1996-09-25 EP claimed
US-5223647-A Using reagent reactive with 4-hydroxy-2,2,6-trimethylcyclohex-ane, selected from halides, silyls, sulfonyl chlorides, carbonyl chlorides, anhydrides, carbonates and chlorocarbonate ; extraction of formed derivative KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1993-06-29 US claimed
JP-63059895-A None JP disclosed
JP-9169686-A None JP disclosed
US-6673583-B2 REDUCTION OF 2,2,6-TRIMETHYL-1,4-CYCLOHEXANEDIONE USING GENETIC ENGINEERED MICROORGANISM INTO WHICH DNA CODES FOR STEREOSPECIFIC OXIDOREDUCTASE ENZYMES, HAVE BEEN TRANSFECTED ROCHE VITAMINS, INC. 2004-01-06 US disclosed
US-20030138921-A1 Recombinantly producing levodione reductase ROCHE VITAMINS, INC. 2003-07-24 US disclosed
US-6534297-B2 Culture product; polypeptide ROCHE VITAMINS, INC. 2003-03-18 US disclosed
US-20020187537-A1 Recombinantly producing levodione reductase DSM NUTRITIONAL PRODUCTS, INC. 2002-12-12 US disclosed
EP-1122315-A1 Corynebacterium aquaticum levodione reductase gene F. HOFFMANN-LA ROCHE AG (CH) 2001-08-08 EP disclosed
US-5777173-A Preparation of pure trans- and cis-4-Hydroxy-2,2,6-trimethylcyclohexan-1-one from isomerc mixtures BASF AKTIENGESELLSCHAFT (DE) 1998-07-07 US disclosed
JP-H09169686-A PRODUCTION OF PURE TRANS-AND CIS-4-HYDROXY-2,2,6-TRIMETHYLCYCLOHEXAN-1-ONE FROM ISOMERIC MIXTURE BASF AG 1997-06-30 JP disclosed
EP-0775685-A1 Process for the isolation of trans- and cis-4-hydroxy-2,2,6-trimethylcyclohexan-1-one from mixtures of these isomers BASF AKTIENGESELLSCHAFT (DE) 1997-05-28 EP disclosed
EP-0775685-A1 Process for the isolation of trans- and cis-4-hydroxy-2,2,6-trimethylcyclohexan-1-one from mixtures of these isomers BASF AKTIENGESELLSCHAFT (DE) 1997-05-28 EP disclosed
EP-0775685-A1 Process for the isolation of trans- and cis-4-hydroxy-2,2,6-trimethylcyclohexan-1-one from mixtures of these isomers BASF AKTIENGESELLSCHAFT (DE) 1997-05-28 EP disclosed
US-5223647-A Using reagent reactive with 4-hydroxy-2,2,6-trimethylcyclohex-ane, selected from halides, silyls, sulfonyl chlorides, carbonyl chlorides, anhydrides, carbonates and chlorocarbonate ; extraction of formed derivative KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1993-06-29 US disclosed
JP-S6359895-A PRODUCTION OF CIS-4-HYDROXY-2,2,6-TRIMETHYLCYCLOHEXANONE NIPPON KAYAKU CO LTD 1988-03-15 JP disclosed
JP-S06359895-A 0001-01-01 JP disclosed