Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.48 |
| ▸ | CCR6 | P51684 | 2/20 | 0.48 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.34 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6677339 | 1.00 | HSP90AA1 (0.48) | HSP90AA1CCR6NFE2L2NPY5RMITF | |
| SCHEMBL6727331 | 1.00 | HSP90AA1 (0.48) | HSP90AA1CCR6NFE2L2NPY5RMITF | |
| SCHEMBL6677987 | 1.00 | HSP90AA1 (0.48) | HSP90AA1CCR6NFE2L2NPY5RMITF | |
| SCHEMBL6683488 | 1.00 | HSP90AA1 (0.48) | HSP90AA1CCR6NFE2L2NPY5RMITF | |
| SCHEMBL6677990 | 0.90 | CCR6 (0.48) | HSP90AA1CCR6NFE2L2MITFEGFR | |
| SCHEMBL6718866 | 0.90 | CCR6 (0.48) | HSP90AA1CCR6NFE2L2MITFEGFR | |
| SCHEMBL6681695 | 0.90 | CCR6 (0.48) | HSP90AA1CCR6NFE2L2MITFEGFR | |
| SCHEMBL6677991 | 0.90 | CCR6 (0.48) | HSP90AA1CCR6NFE2L2MITFEGFR | |
| SCHEMBL6727332 | 0.86 | NFE2L2 (0.39) | HSP90AA1CCR6NFE2L2NPY5REGFR | |
| SCHEMBL6721138 | 0.86 | NFE2L2 (0.39) | HSP90AA1CCR6NFE2L2NPY5REGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6673794-B2 | ANALGESICS, INCOTINENCE, SKIN DISORDERS, ANTIINFLAMMATORY AGENTS | GRUENENTHAL GMBH (DE) | 2004-01-06 | — | — | US | claimed |