Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 19/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 15/20 | 0.46 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6667771 | 0.89 | TLR7 (0.44) | TLR7TLR8NUDT1 | |
| SCHEMBL5031322 | 0.86 | TLR7 (0.40) | TLR7TLR8NUDT1 | |
| SCHEMBL5031335 | 0.84 | TLR7 (0.44) | TLR7TLR8 | |
| SCHEMBL6096708 | 0.83 | TLR7 (0.49) | TLR7TLR8NUDT1 | |
| SCHEMBL29421426 | 0.81 | TLR7 (0.73) | TLR7TLR8NUDT1 | |
| SCHEMBL4565959 | 0.81 | TLR7 (0.43) | TLR7TLR8NUDT1 | |
| SCHEMBL1616712 | 0.81 | TLR7 (0.73) | TLR7TLR8NUDT1 | |
| SCHEMBL29421427 | 0.81 | TLR7 (0.73) | TLR7TLR8NUDT1 | |
| SCHEMBL25180408 | 0.81 | TLR7 (0.52) | TLR7TLR8NUDT1 | |
| SCHEMBL6832787 | 0.81 | TLR7 (0.64) | TLR7TLR8NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040147533-A1 | Sulfonamido substituted imidazopyridines | 3M INNOVATIVE PROPERTIES COMPANY | 2004-07-29 | — | — | US | claimed |
| US-20040019076-A1 | SULFONAMIDO SUBSTITUTED IMIDAZOPYRIDINES | 3M INNOVATIVE PROPERTIES COMPANY | 2004-01-29 | — | — | US | claimed |
| US-6525064-B1 | Immune response modifiers; can induce the biosynthesis of various cytokines; | 3M INNOVATIVE PROPERTIES COMPANY | 2003-02-25 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040147533-A1 | Sulfonamido substituted imidazopyridines | IRF3, EIF2AK2, MYD88 | TLR7 52/4885TLR8 62/4885NUDT1 860/4885 |
| US-20040019076-A1 | SULFONAMIDO SUBSTITUTED IMIDAZOPYRIDINES | IRF3, EIF2AK2, MYD88 | TLR7 52/4885TLR8 62/4885NUDT1 860/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.