SCHEMBL6832787

SCHEMBL6832787

CCOCc1nc2c(N)nc(C)c(C)c2n1CC(C)(C)O

nearest known ligand 0.64

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 19/20 0.64
TLR8 Q9NR97 15/20 0.64
NUDT1 P36639 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22898778 0.88 TLR7 (0.51) TLR7TLR8NUDT1
SCHEMBL29605589 0.88 TLR7 (0.51) TLR7TLR8NUDT1
SCHEMBL25180408 0.88 TLR7 (0.52) TLR7TLR8NUDT1
SCHEMBL22898750 0.85 TLR7 (0.47) TLR7TLR8NUDT1
SCHEMBL29605729 0.85 TLR7 (0.47) TLR7TLR8NUDT1
SCHEMBL29653515 0.85 TLR7 (0.49) TLR7TLR8NUDT1
SCHEMBL22898764 0.83 TLR7 (0.47) TLR7TLR8NUDT1
SCHEMBL22898760 0.83 TLR7 (0.47) TLR7TLR8NUDT1
SCHEMBL6096708 0.83 TLR7 (0.49) TLR7TLR8NUDT1
SCHEMBL22898776 0.83 TLR7 (0.47) TLR7TLR8NUDT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0708772-B1 IMIDAZO [4,5-c]PYRIDIN-4-AMINES MINNESOTA MINING & MFG (US) 2000-08-23 EP claimed
EP-0708772-A1 IMIDAZO [4,5-c]PYRIDIN-4-AMINES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-05-01 EP claimed
US-5494916-A VIRICIDES, AGENTS THAT INDUCE INTERFERON BIOSYNTHESIS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-02-27 US claimed
WO-1995002597-A1 IMIDAZO[4,5-c]PYRIDIN-4-AMINES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-01-26 WO claimed
EP-1651190-B1 FORMULATIONS CONTAINING AN IMMUNE RESPONSE MODIFIER 3M INNOVATIVE PROPERTIES CO (US) 2012-09-19 EP disclosed
US-6743920-B2 CHORINATION REPLACING HYDROXYL GROUPS OF 2,4-DIHYROXY-3-NITROPYRIDINE DERIVATIVE; AMINATION, HYDROXYARYLATION, REDUCTION AND CYCLIZATION; AMINE REPLACEMENT OF PHENOXY FUNCTIONALITY 3M INNOVATIVE PROPERTIES COMPANY 2004-06-01 US disclosed
US-20030232852-A1 Process for imidazo[4,5-c]pyridin-4-amines 3M INNOVATIVE PROPERTIES COMPANY 2003-12-18 US disclosed
EP-0708772-B1 IMIDAZO [4,5-c]PYRIDIN-4-AMINES MINNESOTA MINING & MFG (US) 2000-08-23 EP disclosed
US-5644063-A VIRICIDES AND INDUCTION OF INTERFERON BIOSYNTHESIS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-07-01 US disclosed
US-5494916-A VIRICIDES, AGENTS THAT INDUCE INTERFERON BIOSYNTHESIS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-02-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030232852-A1 Process for imidazo[4,5-c]pyridin-4-amines CPNE4, HTR4, IL4 TLR7 1493/4885TLR8 1290/4885NUDT1 575/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.