SCHEMBL6722159

SCHEMBL6722159

Nc1ccc(O)c2ccn(CCO)c12

nearest known ligand 0.37

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
EP300 Q09472 2/20 0.37
KAT2B Q92831 2/20 0.37
KAT8 Q9H7Z6 2/20 0.37
IDO1 P14902 2/20 0.37
HDAC3 O15379 1/20 0.37
NCOR2 Q9Y618 1/20 0.37
HTR2C P28335 1/20 0.33
HSP90AA1 P07900 1/20 0.32
HSP90AB1 P08238 1/20 0.32
PSMB5 P28074 1/20 0.32
PARP1 P09874 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4949543 0.76 IDO1 (0.35) EP300KAT2BKAT8IDO1HDAC3
SCHEMBL6722510 0.74 IDO1 (0.42) EP300KAT2BKAT8IDO1HDAC3
SCHEMBL12992696 0.72 DBH (0.31) HTR2C
SCHEMBL4952992 0.72 EP300 (0.34) EP300KAT2BKAT8IDO1HDAC3
SCHEMBL4956041 0.72 IDO1 (0.43) EP300KAT2BKAT8IDO1HDAC3
SCHEMBL4956571 0.72 IDO1 (0.43) EP300KAT2BKAT8IDO1HDAC3
SCHEMBL9964970 0.70 IDO1 (0.36) IDO1PARP1
SCHEMBL4953042 0.70 EP300 (0.35) EP300KAT2BKAT8IDO1HDAC3
SCHEMBL4949277 0.68 IDO1 (0.39) EP300KAT2BKAT8IDO1HDAC3
SCHEMBL3245076 0.68 HTR2C (0.66) HTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6673122-B1 CONTAINING OXIDIZER L'ORÉAL (FR) 2004-01-06 US claimed
EP-0861835-B1 Para-aminophenols containing compositions for dyeing of keratin fibres, dyeing process, para-aminophenols and a method for their preparation OREAL (FR) 2002-04-17 EP claimed
US-6203580-B1 OXIDATIVE DYEING L'OREAL (FR) 2001-03-20 US claimed
EP-0861835-A1 Para-aminophenols containing compositions for dyeing of keratin fibres, dyeing process, para-aminophenols and a method for their preparation L'OREAL (FR) 1998-09-02 EP claimed
US-6673122-B1 CONTAINING OXIDIZER L'ORÉAL (FR) 2004-01-06 US disclosed
EP-0861835-B1 Para-aminophenols containing compositions for dyeing of keratin fibres, dyeing process, para-aminophenols and a method for their preparation OREAL (FR) 2002-04-17 EP disclosed
US-6203580-B1 OXIDATIVE DYEING L'OREAL (FR) 2001-03-20 US disclosed
EP-0861835-A1 Para-aminophenols containing compositions for dyeing of keratin fibres, dyeing process, para-aminophenols and a method for their preparation L'OREAL (FR) 1998-09-02 EP disclosed