Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.66 |
| ▸ | HTR6 | P50406 | 6/20 | 0.42 |
| ▸ | CDK4 | P11802 | 4/20 | 0.38 |
| ▸ | CCND1 | P24385 | 4/20 | 0.38 |
| ▸ | ASH1L | Q9NR48 | 3/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4321418 | 0.85 | HTR2C (0.60) | HTR2CHTR6CDK4CCND1ASH1L | |
| SCHEMBL4652431 | 0.84 | HTR2C (0.69) | HTR2CHTR6CDK4CCND1CNR2 | |
| SCHEMBL4651322 | 0.81 | HTR2C (0.65) | HTR2CCDK4CCND1CNR2HTR2A | |
| SCHEMBL13090966 | 0.80 | HTR2C (0.57) | HTR2CHTR6CDK4CCND1CNR2 | |
| SCHEMBL879762 | 0.80 | HTR2C (0.44) | HTR2CHTR6CDK4CCND1ASH1L | |
| SCHEMBL17818954 | 0.80 | NOTUM (0.47) | HTR2CHTR6CDK4CCND1ASH1L | |
| SCHEMBL2038502 | 0.80 | HTR2C (0.63) | HTR2CHTR6CNR2 | |
| SCHEMBL30517485 | 0.80 | HTR2C (0.63) | HTR2CHTR6CDK4CCND1HTR2A | |
| SCHEMBL29751560 | 0.79 | HTR2C (0.63) | HTR2CHTR6HTR2A | |
| SCHEMBL4323537 | 0.79 | HTR2C (0.63) | HTR2CHTR6HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010139878-A2 | DYEING COMPOSITION INCLUDING A SECONDARY PARAPHENYLENEDIAMINE OXIDATION BASE AND A SELECTED COUPLER | L'OREAL (FR) | 2010-12-09 | — | — | WO | claimed |
| EP-1002520-B1 | Composition for oxidative dying of keratinous fibres and dying process therewith | OREAL (FR) | 2008-10-29 | — | — | EP | claimed |
| EP-1342466-B1 | Non-colouring composition containing a precursor and a catalyst for oxidative reaction | OREAL (FR) | 2007-10-17 | — | — | EP | claimed |
| WO-2007071686-A1 | COMPOSITION FOR DYEING KERATIN FIBRES WITH A TETRAAZAPENTAMETHINE CATIONIC DIRECT DYE, AN OXIDATION BASE AND A PARTICULAR COUPLER | L'ORÉAL (FR) | 2007-06-28 | — | — | WO | claimed |
| US-6890362-B2 | Oxidation dyeing composition for keratinous fibers and dyeing method using same | L'OREAL, S.A. (FR) | 2005-05-10 | — | — | US | claimed |
| US-20040016062-A1 | Nondyeing composition containing a precursor and an oxidation reaction catalyst | L'OREAL (FR) | 2004-01-29 | — | — | US | claimed |
| EP-0988021-B1 | KERATIN FIBRE OXIDATION DYEING COMPOSITION AND DYEING METHOD USING SAME | OREAL (FR) | 2003-11-12 | — | — | EP | claimed |
| US-20030009835-A1 | Oxidation dyeing composition for keratinous fibres and dyeing method using same | L'OREAL S.A. (FR) | 2003-01-16 | — | — | US | claimed |
| CN-1372458-A | Oxidation dyeing composition for keratinous fibres and dyeing method using said composition | OREAL (FR) | 2002-10-02 | — | — | CN | claimed |
| US-6395042-B1 | OXIDATION BASE, HETEROCYCLIC COUPLERS FOR OXIDATION COLOR DYE | L'ORÉAL (FR) | 2002-05-28 | — | — | US | claimed |
| CN-1259039-A | Keratin fibre oxidation dyeing composition and dyeing method using same | OREAL (FR) | 2000-07-05 | — | — | CN | claimed |
| CN-1254552-A | Ceratin-fibre composition for oxidation dying and method for dying with solid composition | OREAL (FR) | 2000-05-31 | — | — | CN | claimed |
| EP-1002520-A1 | Composition for oxidative dying of keratinous fibres and dying process therewith | L'OREAL (FR) | 2000-05-24 | — | — | EP | claimed |
| EP-0988021-A1 | KERATIN FIBRE OXIDATION DYEING COMPOSITION AND DYEING METHOD USING SAME | L'OREAL (FR) | 2000-03-29 | — | — | EP | claimed |
| US-5869692-A | COUPLER FOR OXIDATION COLOR DYEING OF HAIR | L'OREAL (FR) | 1999-02-09 | — | — | US | claimed |
| WO-1998055083-A1 | KERATIN FIBRE OXIDATION DYEING COMPOSITION AND DYEING METHOD USING SAME | L'OREAL (FR) | 1998-12-10 | — | — | WO | claimed |
| EP-0754681-B1 | N-substituted 4-hydroxyindole derivatives and compositions for dyeing keratinous fibers containing them | OREAL (FR) | 1998-03-04 | — | — | EP | claimed |
| US-5704948-A | Compositions for dyeing keratinous fibers and keratinous fiber dyeing processes with derivatives of 4-hydroxyindole and oxidation bases | L'OREAL (FR) | 1998-01-06 | — | — | US | claimed |
| WO-1997003049-A1 | N-SUBSTITUTED 4-HYDROXYINDOLE DERIVATIVES AND KERATIN FIBRE DYEING COMPOSITIONS CONTAINING SAME | L'OREAL (FR) | 1997-01-30 | — | — | WO | claimed |
| EP-0754681-A1 | N-substituted 4-hydroxy-indole derivatives and compositions for dyeing keratinous fibers containing them | L'OREAL (FR) | 1997-01-22 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040016062-A1 | Nondyeing composition containing a precursor and an oxidation reaction catalyst | KRT18, CUTA, PPOX | HTR2C 3776/4885HTR6 3602/4885CDK4 3531/4885 |
| US-20030009835-A1 | Oxidation dyeing composition for keratinous fibres and dyeing method using same | KRT18, PPOX, NDUFB5 | HTR2C 3775/4885HTR6 2787/4885CDK4 3054/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.