Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MBNL1 | Q9NR56 | 1/20 | 0.66 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 4/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.64 |
| ▸ | USP2 | O75604 | 4/20 | 0.62 |
| ▸ | TP53 | P04637 | 3/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.62 |
| ▸ | CASP1 | P29466 | 3/20 | 0.62 |
| ▸ | CASP7 | P55210 | 3/20 | 0.62 |
| ▸ | HBB | P68871 | 3/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | PRNP | P04156 | 1/20 | 0.62 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1152761 | 0.98 | ADORA2A (0.68) | MBNL1ADORA2AMEN1KMT2ATDP1 | |
| SCHEMBL13832440 | 0.95 | USP2 (0.66) | MBNL1ADORA2AMEN1KMT2ATDP1 | |
| SCHEMBL17423375 | 0.94 | MBNL1 (0.66) | MBNL1ADORA2AMEN1KMT2ATDP1 | |
| SCHEMBL15061237 | 0.91 | USP2 (0.71) | MBNL1ADORA2AMEN1KMT2ATDP1 | |
| Hydrochloric Acid SCHEMBL15061267 | 0.91 | USP2 (0.73) | MBNL1ADORA2AMEN1KMT2ATDP1 | |
| SCHEMBL1152794 | 0.91 | USP2 (0.71) | MBNL1ADORA2AMEN1KMT2ATDP1 | |
| Hydrochloric Acid SCHEMBL15061230 | 0.91 | USP2 (0.73) | MBNL1ADORA2AMEN1KMT2ATDP1 | |
| SCHEMBL15061283 | 0.91 | USP2 (0.71) | MBNL1ADORA2AMEN1KMT2ATDP1 | |
| SCHEMBL15061323 | 0.91 | USP2 (0.74) | MBNL1ADORA2AMEN1KMT2ATDP1 | |
| SCHEMBL8889975 | 0.90 | ADORA2A (0.68) | MBNL1ADORA2AMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040229898-A1 | Cyclic bis-compounds clearing malformed proteins | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2004-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040229898-A1 | Cyclic bis-compounds clearing malformed proteins | PRNP, PRPH, SCN2A | MBNL1 1644/4885ADORA2A 1810/4885MEN1 1761/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.