Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 10/20 | 0.58 |
| ▸ | THRA | P10827 | 7/20 | 0.58 |
| ▸ | MEN1 | O00255 | 6/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | PPARG | P37231 | 5/20 | 0.58 |
| ▸ | LMNA | P02545 | 5/20 | 0.58 |
| ▸ | USP2 | O75604 | 4/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.58 |
| ▸ | TTR | P02766 | 2/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.58 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.58 |
| ▸ | RXRA | P19793 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | HTR1A | P08908 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.58 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6723726 | 1.00 | THRB (0.58) | THRBTHRAMEN1KMT2APPARG | |
| SCHEMBL10878152 | 0.91 | THRB (0.60) | THRBTHRAMEN1KMT2APPARG | |
| SCHEMBL9056612 | 0.90 | TACR1 (0.49) | THRBTHRAMEN1KMT2APPARG | |
| SCHEMBL10790967 | 0.90 | TACR1 (0.49) | THRBTHRAMEN1KMT2APPARG | |
| SCHEMBL28680811 | 0.89 | PCNA (0.67) | THRBTHRAMEN1KMT2APPARG | |
| SCHEMBL28680813 | 0.89 | PCNA (0.67) | THRBTHRAMEN1KMT2APPARG | |
| SCHEMBL1525929 | 0.88 | THRB (0.57) | THRBTHRAMEN1KMT2APPARG | |
| SCHEMBL468892 | 0.87 | THRB (0.69) | THRBTHRAMEN1KMT2APPARG | |
| SCHEMBL468893 | 0.87 | THRB (0.69) | THRBTHRAMEN1KMT2APPARG | |
| SCHEMBL8731461 | 0.87 | THRB (0.51) | THRBTHRAMEN1KMT2APPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116715597-B | Production process of levothyroxine sodium | 湖北潜龙药业有限公司 | 2025-03-07 | — | — | CN | disclosed |
| CN-116715597-A | Production process of levothyroxine sodium | 湖北潜龙药业有限公司 | 2023-09-08 | — | — | CN | disclosed |
| CN-102199103-B | Improved method for synthesizing L-thyroxine sodium | CHANGZHOU INST ENG TECH | 2013-12-25 | — | — | CN | disclosed |
| CN-102199103-A | Improved method for synthesizing L-thyroxine sodium | CHANGZHOU INST ENG TECH | 2011-09-28 | — | — | CN | disclosed |
| US-6677473-B1 | TREATMENT, PREVENTION OR AMELIORATION OF ONE OR MORE SYMPTOMS OF THROMBOTIC DISORDERS, UNSTABLE ANGINA OR CANCER | CORVAS INTERNATIONAL INC | 2004-01-13 | — | — | US | disclosed |
| WO-2001036351-A2 | PLASMINOGEN ACTIVATOR INHIBITOR ANTAGONISTS RELATED APPLICATIONS | CORVAS INTERNATIONAL, INC. (US) | 2001-05-25 | — | — | WO | disclosed |
| US-4670395-A | Enantioselective hydrolysis of N-acylamino acid esters using a combined enzyme system | THE STANDARD OIL COMPANY (US) | 1987-06-02 | — | — | US | disclosed |