SCHEMBL6726036

SCHEMBL6726036

CCCCc1nc2c(Oc3ccccc3)nc(C)c(C)c2n1CCCCc1cc(C(OCCN(C)C)c2ccccc2)ccc1C(N)=O

nearest known ligand 0.36

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 17/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6724365 0.91 TLR7 (0.43) TLR7
SCHEMBL6095413 0.84 TLR7 (0.40) TLR7
SCHEMBL3353948 0.81 TLR7 (0.46) TLR7
SCHEMBL6093743 0.75 TLR7 (0.50) TLR7
SCHEMBL6097280 0.73 TLR7 (0.55) TLR7
SCHEMBL4793756 0.70 SMN1; SMN2 (0.47) TLR7
SCHEMBL6726102 0.70 TLR7 (0.49) TLR7
SCHEMBL4875215 0.69 TLR7 (0.39) TLR7
SCHEMBL4792366 0.67 HPGD (0.39) TLR7
SCHEMBL4794750 0.66 HPGD (0.39) TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040019076-A1 SULFONAMIDO SUBSTITUTED IMIDAZOPYRIDINES 3M INNOVATIVE PROPERTIES COMPANY 2004-01-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040019076-A1 SULFONAMIDO SUBSTITUTED IMIDAZOPYRIDINES IRF3, EIF2AK2, MYD88 TLR7 52/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.