Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 8/20 | 0.49 |
| ▸ | TLR8 | Q9NR97 | 7/20 | 0.49 |
| ▸ | TLR9 | Q9NR96 | 6/20 | 0.49 |
| ▸ | SLC6A7 | Q99884 | 5/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAP2 | P11137 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6731135 | 0.92 | TLR9 (0.48) | TLR7TLR8TLR9SLC6A7SLC6A3 | |
| SCHEMBL6733538 | 0.89 | TLR9 (0.51) | TLR7TLR8TLR9SLC6A7SLC6A3 | |
| SCHEMBL6737727 | 0.87 | TLR7 (0.48) | TLR7TLR8TLR9SLC6A7SLC6A3 | |
| SCHEMBL6731903 | 0.86 | TLR8 (0.49) | TLR7TLR8TLR9SLC6A7SLC6A3 | |
| SCHEMBL6729747 | 0.84 | TLR8 (0.41) | TLR7TLR8TLR9MAPTMEN1 | |
| SCHEMBL6736204 | 0.77 | TLR8 (0.39) | TLR7TLR8TLR9MEN1KMT2A | |
| SCHEMBL6729450 | 0.75 | F10 (0.50) | MAPTMEN1KMT2AMAP2ALDH1A1 | |
| SCHEMBL6726229 | 0.73 | TLR8 (0.41) | TLR7TLR8TLR9MAPTMEN1 | |
| SCHEMBL6737185 | 0.73 | F10 (0.68) | — | |
| SCHEMBL6731390 | 0.72 | F10 (0.49) | TLR7TLR8TLR9SLC6A7SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6747023-B1 | INHIBITORS FOR ACTIVATED COAGULATION FACTOR X, COAGULATION SUPPRESSORS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2004-06-08 | — | — | US | disclosed |
| US-20040082611-A1 | Anticoagulants; brain disorders; respiratory system disorders; side effect reduction | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2004-04-29 | — | — | US | disclosed |
| EP-1104754-A1 | NOVEL SULFONYL DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2001-06-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082611-A1 | Anticoagulants; brain disorders; respiratory system disorders; side effect reduction | F2, CYC1, SULT2A1 | TLR7 3713/4885TLR8 4146/4885TLR9 4173/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.