SCHEMBL67273

SCHEMBL67273

COc1cc2oc(=O)cc(CBr)c2cc1OC

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.47
NQO1 P15559 1/20 0.47
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
NPC1 O15118 1/20 0.46
ACHE P22303 1/20 0.46
DYRK1A Q13627 1/20 0.46
KDM4E B2RXH2 7/20 0.45
ALDH1A1 P00352 5/20 0.45
MAPT P10636 2/20 0.45
CYP2D6 P10635 2/20 0.44
CYP3A4 P08684 2/20 0.44
CYP2C9 P11712 1/20 0.44
HPGD P15428 3/20 0.44
HSD17B10 Q99714 3/20 0.44
MAPK1 P28482 1/20 0.44
HSD17B3 P37058 1/20 0.43
PDE4D Q08499 1/20 0.43
GLA P06280 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31344274 1.00 MCL1 (0.47) MCL1NQO1MEN1KMT2ANPC1
SCHEMBL4086139 0.88 MEN1 (0.48) MCL1NQO1MEN1KMT2ANPC1
SCHEMBL8728352 0.84 KDM4E (0.57) MEN1KMT2AKDM4EALDH1A1MAPT
SCHEMBL24025683 0.84 MCL1 (0.47) MCL1NQO1MEN1KMT2ANPC1
SCHEMBL12919918 0.84 MCL1 (0.61) MCL1NQO1MEN1KMT2ANPC1
SCHEMBL30696154 0.83 SMN1; SMN2 (0.48) MCL1NQO1MEN1KMT2ANPC1
SCHEMBL19134008 0.81 MCL1 (0.45) MCL1NQO1MEN1KMT2ANPC1
SCHEMBL869935 0.80 KDM4E (0.67) MCL1NQO1KDM4EALDH1A1MAPT
SCHEMBL12221067 0.80 CYP3A4 (0.53) MCL1NQO1ACHEKDM4EALDH1A1
SCHEMBL13609432 0.80 MEN1 (0.47) MCL1NQO1MEN1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5663029-A DEVELOPMENT OF LATENT IMAGE, TRANSFERRING TO FORM RECORDING SHEETS, COATING A SUBSTRATE USING POLYMERS XEROX CORPORATION (US) 1997-09-02 US claimed
EP-0620500-A2 Resist and pattern formation using the same HITACHI, LTD. (JP) 1994-10-19 EP claimed
JP-5000945-A None JP disclosed
EP-4443155-B1 ENCAPSULATED PRE-ANALYTIC WORKFLOWS FOR FLOW-THROUGH DEVICES, LIQUID CHROMATOGRAPHY AND MASS SPECTROMETRIC ANALYSIS WATERS TECHNOLOGIES CORP (US) 2026-05-13 EP disclosed
US-12487210-B2 Encapsulated pre-analytic workflows for flow-through devices, liquid chromatography and mass spectrometric analysis WATERS TECHNOLOGIES CORPORATION (US) 2025-12-02 US disclosed
US-12194084-B2 Multi-subunit vaccines to elicit both MHC- and CD1-restricted T cell responses NORTHWESTERN UNIVERSITY (US) 2025-01-14 US disclosed
US-12117450-B2 DNA-cage erasable labels for fluorescence-based pathology OHIO STATE INNOVATION FOUNDATION (US) 2024-10-15 US disclosed
EP-4443155-A2 ENCAPSULATED PRE-ANALYTIC WORKFLOWS FOR FLOW-THROUGH DEVICES, LIQUID CHROMATOGRAPHY AND MASS SPECTROMETRIC ANALYSIS Waters Technologies Corporation (US) 2024-10-09 EP disclosed
EP-3491374-B1 ENCAPSULATED PRE-ANALYTIC WORKFLOW REAGENTS FOR FLOW-THROUGH DEVICES, LIQUID CHROMATOGRAPHY AND MASS SPECTROMETRIC ANALYSIS WATERS TECHNOLOGIES CORP (US) 2024-10-09 EP disclosed
CN-115820598-B Haloalkane dehalogenase DhaA mutant with improved tolerance to organic solvents and application thereof 天津大学 2024-07-09 CN disclosed
CN-115820598-A Haloalkane dehalogenase DhaA mutant with improved organic solvent tolerance and application thereof 天津大学 2023-03-21 CN disclosed
WO-1997026300-A1 COMBINATORIAL PROCESS FOR PREPARING SUBSTITUTED INDANE LIBRARIES ELI LILLY AND COMPANY (US) 1997-07-24 WO disclosed
EP-0703218-A1 Pyrrolidinyl di-carboxylic acid derivatives as metabotropic glutamate receptor antagonists ELI LILLY AND COMPANY (US) 1996-03-27 EP disclosed
WO-1996005828-A1 PYRROLIDINYL DI-CARBOXYLIC ACID DERIVATIVES AS METABOTROPIC GLUTAMATE RECEPTOR ANTAGONISTS ELI LILLY AND COMPANY (US) 1996-02-29 WO disclosed
EP-0620500-A2 Resist and pattern formation using the same HITACHI, LTD. (JP) 1994-10-19 EP disclosed
EP-0534316-A1 Use of alkylated polyethylenimines to concentrate bile acids HOECHST AKTIENGESELLSCHAFT (DE) 1993-03-31 EP disclosed
JP-H05945-A CARCINOSTATIC AGENT NIKKO KYODO CO LTD 1993-01-08 JP disclosed
WO-1992012635-A1 METHODS OF TRANSCRIPTIONALLY MODULATING GENE EXPRESSION OF VIRAL GENES AND OTHER GENES ONCOGENE SCIENCE, INC. (US) 1992-08-06 WO disclosed
EP-0462229-A4 CHEMICALLY MODIFIED CD4 PEPTIDE FRAGMENTS HAVING ANTI-RETROVIRAL PROPERTIES 1992-03-11 EP disclosed
EP-0462229-A1 CHEMICALLY MODIFIED CD4 PEPTIDE FRAGMENTS HAVING ANTI-RETROVIRAL PROPERTIES GENELABS, INCORPORATED (US) 1991-12-27 EP disclosed