Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 2/20 | 0.32 |
| ▸ | ACACA | Q13085 | 2/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CYBB | P04839 | 1/20 | 0.30 |
| ▸ | NOX5 | Q96PH1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18873813 | 1.00 | PGR (0.36) | PGRS1PR1S1PR5ACACBACACA | |
| SCHEMBL16776718 | 1.00 | PGR (0.36) | PGRS1PR1S1PR5ACACBACACA | |
| SCHEMBL6727390 | 0.91 | ACACB (0.39) | ACACBACACAPTGS1PTGS2 | |
| SCHEMBL18874081 | 0.91 | ACACB (0.39) | ACACBACACAPTGS1PTGS2 | |
| SCHEMBL6727294 | 0.91 | ACACB (0.36) | PGRACACBACACA | |
| SCHEMBL13068675 | 0.91 | ACACB (0.36) | PGRACACBACACA | |
| SCHEMBL18874236 | 0.91 | ACACB (0.36) | PGRACACBACACA | |
| SCHEMBL18873860 | 0.88 | PDE3B (0.34) | ACACBACACAMEN1KMT2A | |
| SCHEMBL6727610 | 0.88 | PDE3B (0.34) | ACACBACACAMEN1KMT2A | |
| SCHEMBL6727393 | 0.87 | KLKB1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2173755-B1 | NOVEL HERBICIDES | SYNGENTA LTD (GB) | 2017-05-17 | — | — | EP | disclosed |
| US-8940913-B2 | Herbicides | SYNGENTA CROP PROTECTION, LLC (US) | 2015-01-27 | — | — | US | disclosed |
| US-8940913-B2 | Herbicides | SYNGENTA CROP PROTECTION, LLC (US) | 2015-01-27 | — | — | US | disclosed |
| US-8835657-B2 | Cyclopentanedione compounds and their use as insecticides, acaricides and/or fungicides | BAYER CROPSCIENCE AG (DE) | 2014-09-16 | — | — | US | disclosed |
| US-8835657-B2 | Cyclopentanedione compounds and their use as insecticides, acaricides and/or fungicides | BAYER CROPSCIENCE AG (DE) | 2014-09-16 | — | — | US | disclosed |
| US-20120142529-A1 | NOVEL HERBICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2012-06-07 | — | — | US | disclosed |
| US-20120142529-A1 | NOVEL HERBICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2012-06-07 | — | — | US | disclosed |
| US-20120123129-A1 | Cyclopentanedione Compounds and Their Use as Insecticides, Acaricides and/or Fungicides | BAYER CROPSCIENCE AG (DE) | 2012-05-17 | — | — | US | disclosed |
| US-20120123129-A1 | Cyclopentanedione Compounds and Their Use as Insecticides, Acaricides and/or Fungicides | BAYER CROPSCIENCE AG (DE) | 2012-05-17 | — | — | US | disclosed |
| WO-2009019015-A1 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2009-02-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120123129-A1 | Cyclopentanedione Compounds and Their Use as Insecticides, Acaricides and/or Fungicides | CYP51A1, CYP1B1, CBR3 | PGR 3209/4885S1PR1 1099/4885S1PR5 1621/4885 |
| US-20120142529-A1 | NOVEL HERBICIDES | DDT, CYP4X1, CYP1B1 | PGR 4626/4885S1PR1 3494/4885S1PR5 4209/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.