Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 4/20 | 0.35 |
| ▸ | FDPS | P14324 | 2/20 | 0.34 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | METAP1 | P53582 | 1/20 | 0.32 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.32 |
| ▸ | LAP3 | P28838 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25175095 | 0.96 | CYP3A4 (0.37) | CYP3A4L3MBTL1CA2FDPSSMPD1 | |
| SCHEMBL6908494 | 0.96 | CYP3A4 (0.37) | CYP3A4L3MBTL1CA2FDPSSMPD1 | |
| SCHEMBL7195333 | 0.96 | CYP3A4 (0.37) | CYP3A4L3MBTL1CA2FDPSSMPD1 | |
| SCHEMBL215423 | 0.96 | CYP3A4 (0.37) | CYP3A4L3MBTL1CA2FDPSSMPD1 | |
| SCHEMBL5692944 | 0.83 | CYP3A4 (0.44) | CYP3A4L3MBTL1CA2FDPSSMPD1 | |
| SCHEMBL5692946 | 0.80 | PTPN1 (0.51) | CYP3A4L3MBTL1FDPSSMPD1PTPN1 | |
| SCHEMBL4178393 | 0.79 | PTPN1 (0.50) | CYP3A4L3MBTL1FDPSSMPD1PTPN1 | |
| SCHEMBL9444627 | 0.76 | SMPD1 (0.46) | CYP3A4L3MBTL1FDPSSMPD1PTPN1 | |
| SCHEMBL10783602 | 0.76 | PTPN1 (0.59) | FDPSSMPD1PTPN1S1PR2S1PR1 | |
| SCHEMBL2150629 | 0.74 | SMPD1 (0.61) | FDPSSMPD1PTPN1S1PR2S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8067503-B2 | Process for producing blends of syndiotactic, 1,2-polybutadiene and rubbery elastomers | BRIDGESTONE CORPORATION (JP) | 2011-11-29 | — | — | US | disclosed |
| US-6545107-B2 | Reaction product of an molybdenum- containing compound, a silyl phosphonate; and an organoaluminum compound catalyst used for polymerizing conjugated diene monomer | BRIDGESTONE CORPORATION (JP) | 2003-04-08 | — | — | US | disclosed |