Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 5/20 | 0.35 |
| ▸ | FDPS | P14324 | 2/20 | 0.34 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25175095 | 0.96 | CYP3A4 (0.37) | CYP3A4L3MBTL1CA2FDPSSMPD1 | |
| SCHEMBL215423 | 0.96 | CYP3A4 (0.37) | CYP3A4L3MBTL1CA2FDPSSMPD1 | |
| SCHEMBL672785 | 0.96 | CYP3A4 (0.37) | CYP3A4L3MBTL1CA2FDPSSMPD1 | |
| SCHEMBL7195333 | 0.96 | CYP3A4 (0.37) | CYP3A4L3MBTL1CA2FDPSSMPD1 | |
| SCHEMBL5692944 | 0.83 | CYP3A4 (0.44) | CYP3A4L3MBTL1CA2FDPSSMPD1 | |
| SCHEMBL5692946 | 0.80 | PTPN1 (0.51) | CYP3A4L3MBTL1FDPSSMPD1PTPN1 | |
| SCHEMBL4178393 | 0.79 | PTPN1 (0.50) | CYP3A4L3MBTL1FDPSSMPD1PTPN1 | |
| SCHEMBL9444627 | 0.76 | SMPD1 (0.46) | CYP3A4L3MBTL1FDPSSMPD1PTPN1 | |
| SCHEMBL10783602 | 0.76 | PTPN1 (0.59) | FDPSSMPD1PTPN1 | |
| SCHEMBL672778 | 0.76 | SMPD1 (0.39) | CYP3A4L3MBTL1CA2FDPSSMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040242780-A1 | using a catalyst that is based on a chromium-containing compound, a hydrogen phosphite, and an organomagnesium compound, or a catalyst based on a molybdenum or iron-compound, a hydrogen phosphite and organoaluminum compound; tire sidewalls; obviates the need for high-temperature mixing | BRIDGESTONE CORPORATION (JP) | 2004-12-02 | — | — | US | disclosed |