SCHEMBL672786

SCHEMBL672786

CCCCCCCC(c1cc(C)cc(-n2nc3ccc(Cl)cc3n2)c1O)c1cc(C)cc(-n2nc3ccc(Cl)cc3n2)c1O

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ NPC1 O15118 2/20 0.44
▸ RAB9A P51151 2/20 0.44
▸ LMNA P02545 1/20 0.36
▸ POLB P06746 1/20 0.36
▸ CNR1 P21554 3/20 0.34
▸ CNR2 P34972 3/20 0.34
▸ PDE5A O76074 1/20 0.34
▸ KDM4E B2RXH2 2/20 0.33
▸ ADORA3 P0DMS8 3/20 0.32
▸ ALDH1A1 P00352 1/20 0.32
▸ CYP1A2 P05177 1/20 0.32
▸ CYP2C9 P11712 1/20 0.32
▸ HPGD P15428 1/20 0.32
▸ CYP2C19 P33261 1/20 0.32
▸ PPARA Q07869 2/20 0.32
▸ TP53 P04637 1/20 0.31
▸ MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL672068 0.88 NPC1 (0.52) NPC1RAB9ALMNAPOLBPDE5A
SCHEMBL31614335 0.88 NPC1 (0.52) NPC1RAB9ALMNAPOLBPDE5A
SCHEMBL19332461 0.83 NPC1 (0.46) NPC1RAB9ALMNAPOLBKDM4E
SCHEMBL994987 0.81 NPC1 (0.47) NPC1RAB9ALMNAPOLBCNR1
SCHEMBL9628354 0.81 NPC1 (0.47) NPC1RAB9ALMNAPOLBCNR1
SCHEMBL29407323 0.81 NPC1 (0.47) NPC1RAB9ALMNAPOLBCNR1
SCHEMBL9628860 0.81 NPC1 (0.47) NPC1RAB9ALMNAPOLBCNR1
SCHEMBL9628396 0.81 NPC1 (0.47) NPC1RAB9ALMNAPOLBCNR1
SCHEMBL10743175 0.81 NPC1 (0.47) NPC1RAB9ALMNAPOLBCNR1
SCHEMBL9628497 0.81 NPC1 (0.47) NPC1RAB9ALMNAPOLBCNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024117159-A1 RESIN COMPOSITION, PELLET, MOLDED ARTICLE, AND METHOD FOR PRODUCING RESIN COMPOSITION 三菱ケミカル株式会社 2024-06-06 — — WO disclosed
WO-2024117158-A1 RESIN COMPOSITION, PELLETS AND MOLDED ARTICLE 三菱ケミカル株式会社 2024-06-06 — — WO disclosed
WO-2024038853-A1 RESIN COMPOSITION, PELLETS, AND MOLDED ARTICLE 三菱ケミカル株式会社 2024-02-22 — — WO disclosed
WO-2023214487-A1 RESIN COMPOSITION, MOLDED ARTICLE, AND METHOD FOR PRODUCING RESIN COMPOSITION 三菱ケミカル株式会社 2023-11-09 — — WO disclosed
US-7968632-B2 Polycarbonate resin composition and process for producing thereof MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2011-06-28 — — US disclosed
EP-1892266-B1 POLYCARBONATE RESIN COMPOSITION AND MOLDED ARTICLES MITSUBISHI ENG PLASTICS CORP (JP) 2010-07-21 — — EP disclosed
US-20090186967-A1 Polycarbonate resin composition and process for producing thereof MITSUBISHI ENGINEERING PLASTICS CORPORATION (JP) 2009-07-23 — — US disclosed
EP-1892266-A1 POLYCARBONATE RESIN COMPOSITION AND MOLDED ARTICLES Mitsubishi Engineering-Plastics Corporation (JP) 2008-02-27 — — EP disclosed
US-6762250-B2 TRANSPARENCY, FLUIDITY; CONTAINING POLYSILOXANE HAVING AT LEAST AROMATIC HYDROCARBON FUNCTIONALITY, CARBOXYLIC ACID ESTER AND/OR ETHER LINKAGES AND PHOSPHORIC ESTER GROUP ATTACHMENT MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2004-07-13 — — US disclosed
US-6727294-B2 RADIATION TRANSPARENT MOLDING MATERIALS MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2004-04-27 — — US disclosed
US-20040054116-A1 Polycarbonate resin composition MITSUBISHI ENGINEERING-PLASTICS CORPORATION 2004-03-18 — — US disclosed
US-20010034419-A1 Radiation transparent molding materials MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2001-10-25 — — US disclosed
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