Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | DAO | P14920 | 3/20 | 0.43 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | KMO | O15229 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 2/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.37 |
| ▸ | TYK2 | P29597 | 1/20 | 0.37 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7927678 | 0.87 | DPP4 (0.44) | DPP4DAOCLCN2ALDH1A1KDM4E | |
| SCHEMBL3236266 | 0.83 | CLCN2 (0.50) | DPP4DAOCLCN2ALDH1A1KDM4E | |
| SCHEMBL31193466 | 0.82 | DPP4 (0.60) | DPP4ALDH1A1KDM4EHSD17B10NOTUM | |
| Hydrochloric Acid SCHEMBL3583525 | 0.81 | CLCN2 (0.49) | DPP4DAOCLCN2ALDH1A1KDM4E | |
| SCHEMBL936925 | 0.81 | DAO (0.46) | DAOALDH1A1NOTUMKMOHPGD | |
| SCHEMBL19585173 | 0.79 | DAO (0.44) | DAOCLCN2ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL979367 | 0.79 | CLCN2 (0.47) | DPP4DAOCLCN2ALDH1A1KDM4E | |
| SCHEMBL6725047 | 0.78 | DAO (0.43) | DAOALDH1A1KDM4ENOTUMHPGD | |
| SCHEMBL2926338 | 0.78 | NOTUM (0.38) | DPP4DAOCLCN2NOTUMKDR | |
| SCHEMBL30054183 | 0.78 | DAO (0.43) | DAOALDH1A1KDM4ENOTUMHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6677479-B2 | REACTING A HALOGENATED BENZENE COMPOUND WITH ALDEHYDE; SOLVENT EXTRACTION; PURIFICATION | CLARIANT FINANCE LBVI LIMITED (VG) | 2004-01-13 | — | — | US | disclosed |
| US-20030092930-A1 | Substituted fluoroaromatics, process for preparing them and their use | CLARIANT GMBH | 2003-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030092930-A1 | Substituted fluoroaromatics, process for preparing them and their use | CYP2F1, CYP1A1, CYP4X1 | DPP4 4490/4885DAO 681/4885CLCN2 1283/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.