Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.64 |
| ▸ | TSHR | P16473 | 4/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.52 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.52 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6729581 | 1.00 | ALDH1A1 (0.64) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL6555938 | 0.93 | ALDH1A1 (0.58) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL6736087 | 0.93 | ALDH1A1 (0.58) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL27789877 | 0.93 | ALDH1A1 (0.58) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL27937622 | 0.93 | ALDH1A1 (0.75) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL29447720 | 0.91 | ALDH1A1 (0.73) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL29447771 | 0.90 | ALDH1A1 (0.71) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL8159950 | 0.89 | ALDH1A1 (0.82) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL10338877 | 0.89 | ALDH1A1 (0.82) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL10338880 | 0.89 | ALDH1A1 (0.82) | ALDH1A1TSHRLMNACYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040209969-A1 | Polyisocyanate polyaddition products | ARLT ANDREAS | 2004-10-21 | — | — | US | disclosed |
| US-6794421-B2 | comprising hydrophobic compounds plus at least one further compound and/or derivative thereof reactive toward primary amines, compound being selected from cyclic sulfonic esters and sulfones and mixtures thereof | BASF AKTIENGESELLSCHAFT (DE) | 2004-09-21 | — | — | US | disclosed |
| US-20030130366-A1 | Polyisocyanate polyaddition products | ARLT ANDREAS (DE) | 2003-07-10 | — | — | US | disclosed |
| US-6495611-B1 | MATTRESS OR FURNITURE UPHOLSTERY OR CARPET BACKING COMPRISING A FLEXIBLE POLYURETHANE FOAM COMPRISING HYDROPHOBIC COMPOUNDS PLUS AT LEAST ONE CYCLODEXTRIN, RESORCINARENE, CYCLOPHANE AND/OR CYCLOCALIXARENE | BASF AKTIENGESELLSCHAFT (DE) | 2002-12-17 | — | — | US | disclosed |