⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| E968 SCHEMBL30287920 | 1.00 | — | — | |
| E968 SCHEMBL13727065 | 1.00 | LMNA (0.67) | — | |
| E968 SCHEMBL36228 | 1.00 | — | — | |
| E968 SCHEMBL1697009 | 1.00 | LMNA (0.67) | — | |
| E968 SCHEMBL10427336 | 1.00 | — | — | |
| E968 SCHEMBL121807 | 1.00 | — | — | |
| E968 SCHEMBL2723809 | 1.00 | LMNA (0.67) | — | |
| E968 SCHEMBL17062 | 1.00 | — | — | |
| E968 SCHEMBL17766 | 1.00 | — | — | |
| E968 SCHEMBL9566824 | 1.00 | LMNA (0.67) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130012466-A1 | COLCHICINE NEOGLYCOSIDES AND METHODS FOR THEIR SYNTHESIS AND USE | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2013-01-10 | — | — | US | disclosed |
| EP-2052250-B1 | SOLID-PHASE DETECTION OF TERMINAL MONOSACCHARIDES CLEAVED FROM GLYCOSYLATED SUBSTRATES | MERCK PATENT GMBH (DE) | 2012-05-16 | — | — | EP | disclosed |
| US-8076466-B2 | Saccharidic fluorescent substrates, their process of preparation and their use | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2011-12-13 | — | — | US | disclosed |
| EP-2351777-A1 | ANTI-MUC1 ANTIBODY | Shionogi & Co., Ltd. (JP) | 2011-08-03 | — | — | EP | disclosed |
| US-7939230-B2 | Overcoat layer comprising core-shell fluorinated particles | XEROX CORPORATION (US) | 2011-05-10 | — | — | US | disclosed |
| US-7928077-B2 | Alpha-galactosyl ceramide analogs and their use as immunotherapies | ACADEMIA SINICA (TW) | 2011-04-19 | — | — | US | disclosed |
| US-20100047828-A1 | SOLID-PHASE DETECTION OF TERMINAL MONOSACCHARIDES CLEAVED FROM GLYCOSYLATED SUBSTRATES | MERCK PATENT GESELLSCHAFT (DE) | 2010-02-25 | — | — | US | disclosed |
| US-20100008954-A1 | Alpha-galactosyl ceramide analogs and their use as immunotherapies | ACADEMIA SINICA (TW) | 2010-01-14 | — | — | US | disclosed |
| EP-1124855-B1 | COMPOSITIONS AND METHODS FOR TREATING POLYCYSTIC KIDNEY DISEASE | GENZYME CORP (US) | 2009-08-19 | — | — | EP | disclosed |
| US-20080171787-A1 | COLCHICINE NEOGLYCOSIDES AND METHODS FOR THEIR SYNTHESIS AND USE | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2008-07-17 | — | — | US | disclosed |
| EP-1862466-A2 | Arrays with cleavable linkers | The Scripps Research Institute (US) | 2007-12-05 | — | — | EP | disclosed |
| WO-2007129221-A2 | COMPOSITIONS COMPRISING AN EPI-INOSITOL COMPOUNDS AND METHODS FOR TREATMENT OF DISORDERS OF PROTEIN AGGREGATION | WARATAH PARMACEUTICALS INC (CA) | 2007-11-15 | — | — | WO | disclosed |