Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 1/20 | 0.73 |
| ▸ | F11 | P03951 | 1/20 | 0.73 |
| ▸ | ELANE | P08246 | 5/20 | 0.73 |
| ▸ | KLK7 | P49862 | 3/20 | 0.73 |
| ▸ | F2 | P00734 | 1/20 | 0.59 |
| ▸ | HTRA1 | Q92743 | 6/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nostopeptin Bn920 SCHEMBL13518016 | 0.95 | KLK7 (0.74) | PLGF11ELANEKLK7F2 | |
| Micropeptin T1 SCHEMBL29885250 | 0.92 | PLG (0.84) | PLGF11ELANEKLK7F2 | |
| SCHEMBL6756788 | 0.90 | ELANE (0.62) | PLGF11ELANEKLK7F2 | |
| SCHEMBL13815042 | 0.89 | KLK7 (0.72) | PLGF11ELANEKLK7F2 | |
| Micropeptin C SCHEMBL29884628 | 0.88 | PLG (0.87) | PLGF11ELANEKLK7F2 | |
| Micropeptin D SCHEMBL29884439 | 0.88 | PLG (0.86) | PLGF11ELANEKLK7F2 | |
| SCHEMBL29884697 | 0.88 | KLK7 (0.79) | PLGF11ELANEKLK7F2 | |
| SCHEMBL6729492 | 0.87 | KLK7 (0.95) | PLGF11ELANEKLK7F2 | |
| SCHEMBL6730022 | 0.87 | KLK7 (0.88) | PLGF11ELANEKLK7F2 | |
| Cyanopeptolin 963A SCHEMBL29884137 | 0.86 | PLG (0.78) | PLGF11ELANEKLK7F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8178650-B2 | Cyclic depsipeptides | NOVARTIS AG (CH) | 2012-05-15 | — | — | US | disclosed |
| US-20090156472-A1 | Cyclic Depsipeptides | NOVARTIS AG (CH) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156472-A1 | Cyclic Depsipeptides | SERPINB1, ELANE, KLK7 | PLG 48/4885F11 173/4885ELANE 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.