SCHEMBL6730210

SCHEMBL6730210

CCOC(F)(OC(C)=O)C(F)F

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.34
LMNA P02545 1/20 0.34
HSD17B10 Q99714 1/20 0.34
GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10180069 0.78
SCHEMBL10180921 0.72
SCHEMBL19812422 0.69 ALDH1A1 (0.41) ALDH1A1LMNAHSD17B10GAA
SCHEMBL4863900 0.69 GAA (0.36) ALDH1A1GAA
SCHEMBL783715 0.69 ALDH1A1 (0.43) ALDH1A1LMNAHSD17B10GAA
SCHEMBL11128475 0.67 GAA (0.44) ALDH1A1LMNAHSD17B10GAA
SCHEMBL9625829 0.67 GAA (0.44) ALDH1A1LMNAHSD17B10GAA
SCHEMBL10441557 0.66 ALDH1A1 (0.40) ALDH1A1LMNAHSD17B10GAA
SCHEMBL11444039 0.66 GAA (0.33) GAA
SCHEMBL29051399 0.66 GAA (0.33) GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6677085-B2 SHORT CIRCUITING PREVENTION SOLVAY FLUOR UND DERIVATE GMBH (DE) 2004-01-13 US disclosed