Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4844804 | 0.90 | LMNA (0.42) | LMNAALDH1A1KDM4ETHRBMAPK1 | |
| SCHEMBL4248406 | 0.87 | LMNA (0.44) | LMNAALDH1A1KDM4ETHRB | |
| SCHEMBL3967264 | 0.87 | LMNA (0.44) | LMNAALDH1A1KDM4ETHRB | |
| SCHEMBL32670321 | 0.87 | LMNA (0.44) | LMNAALDH1A1KDM4ETHRB | |
| SCHEMBL11416016 | 0.87 | USP2 (0.46) | LMNAALDH1A1KDM4EMAPK1TDP1 | |
| SCHEMBL9499250 | 0.87 | USP2 (0.46) | LMNAALDH1A1KDM4EMAPK1TDP1 | |
| SCHEMBL3673713 | 0.87 | USP2 (0.46) | LMNAKDM4EMAPK1TDP1 | |
| SCHEMBL1288234 | 0.87 | USP2 (0.46) | LMNAKDM4EMAPK1TDP1 | |
| SCHEMBL11405257 | 0.87 | USP2 (0.46) | LMNAKDM4EMAPK1TDP1 | |
| SCHEMBL3669886 | 0.87 | USP2 (0.46) | LMNAKDM4EMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6673890-B1 | DETERGENTS, DISPERSANTS | BASF AKTIENGESELLSCHAFT (DE) | 2004-01-06 | — | — | US | claimed |
| EP-1198492-B1 | ZWITTERIONIC POLYAMINES AND A PROCESS FOR THEIR PRODUCTION | BASF AG (DE) | 2003-10-08 | — | — | EP | claimed |
| US-6673890-B1 | DETERGENTS, DISPERSANTS | BASF AKTIENGESELLSCHAFT (DE) | 2004-01-06 | — | — | US | disclosed |
| EP-1198492-B1 | ZWITTERIONIC POLYAMINES AND A PROCESS FOR THEIR PRODUCTION | BASF AG (DE) | 2003-10-08 | — | — | EP | disclosed |