Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | FABP3 | P05413 | 9/20 | 0.42 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | BBOX1 | O75936 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dodecanoate SCHEMBL4452703 | 0.89 | FABP3 (0.58) | CA1FABP3 | |
| Stearic Acid SCHEMBL4446741 | 0.89 | FABP3 (0.58) | CA1FABP3 | |
| SCHEMBL673674 | 0.83 | CA1 (0.39) | CA1FABP3FFAR3HDAC3HDAC1 | |
| SCHEMBL17796050 | 0.80 | CA1 (0.48) | CA1FFAR3HDAC3HDAC1HDAC2 | |
| Adipic Acid SCHEMBL8076329 | 0.78 | CA1 (0.57) | CA1FABP3FFAR3HDAC3HDAC1 | |
| Azelaic Acid SCHEMBL7627274 | 0.76 | CA1 (0.55) | CA1FABP3FFAR3HDAC3HDAC1 | |
| Sebacic Acid SCHEMBL17961672 | 0.76 | CA1 (0.55) | CA1FABP3FFAR3HDAC3HDAC1 | |
| Octanedioate SCHEMBL17961688 | 0.76 | CA1 (0.55) | CA1FABP3FFAR3HDAC3HDAC1 | |
| Adipic Acid SCHEMBL9820842 | 0.74 | CA1 (0.58) | CA1FABP3FFAR3HDAC3HDAC1 | |
| Adipic Acid SCHEMBL3137967 | 0.74 | CA1 (0.58) | CA1FABP3FFAR3HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3456746-B1 | TERMINAL-MODIFIED CONJUGATED DIENE-BASED POLYMER, RUBBER COMPOSITION, AND RUBBER ARTICLE | BRIDGESTONE CORP (JP) | 2023-04-19 | — | — | EP | disclosed |
| EP-3851489-A1 | MODIFIED MULTI-COMPONENT COPOLYMER, RUBBER COMPOSITION, RESIN COMPOSITION, TIRE AND RESIN PRODUCT | BRIDGESTONE CORPORATION (JP) | 2021-07-21 | — | — | EP | disclosed |
| US-10875937-B2 | Terminal-modified conjugated diene polymer, rubber composition and rubber article | BRIDGESTONE CORPORATION (JP) | 2020-12-29 | — | — | US | disclosed |
| CN-109071685-B | Terminal-modified conjugated diene polymer, rubber composition, and rubber article | 株式会社普利司通 | 2020-12-01 | — | — | CN | disclosed |
| US-20190161571-A1 | TERMINAL-MODIFIED CONJUGATED DIENE POLYMER, RUBBER COMPOSITION, RUBBER PRODUCT AND METHOD FOR MANUFACTURING TERMINAL-MODIFIED CONJUGATED DIENE POLYMER | BRIDGESTONE CORPORATION (JP) | 2019-05-30 | — | — | US | disclosed |
| US-20190153123-A1 | TERMINAL-MODIFIED CONJUGATED DIENE POLYMER, RUBBER COMPOSITION AND RUBBER ARTICLE | BRIDGESTONE CORPORATION (JP) | 2019-05-23 | — | — | US | disclosed |
| EP-3466985-A1 | TERMINALLY MODIFIED CONJUGATED DIENE POLYMER, RUBBER COMPOSITION, RUBBER PRODUCT, AND METHOD FOR PRODUCING TERMINALLY MODIFIED CONJUGATED DIENE POLYMER | Bridgestone Corporation (JP) | 2019-04-10 | — | — | EP | disclosed |
| EP-3456746-A1 | TERMINAL-MODIFIED CONJUGATED DIENE-BASED POLYMER, RUBBER COMPOSITION, AND RUBBER ARTICLE | Bridgestone Corporation (JP) | 2019-03-20 | — | — | EP | disclosed |
| US-10131722-B2 | Method for preparing terminal-modified conjugated diene polymer, terminal-modified conjugated diene polymer, rubber composition and tire | BRIDGESTONE CORPORATION (JP) | 2018-11-20 | — | — | US | disclosed |
| US-20170275400-A1 | METHOD FOR PREPARING TERMINAL-MODIFIED CONJUGATED DIENE POLYMER, TERMINAL-MODIFIED CONJUGATED DIENE POLYMER, RUBBER COMPOSITION AND TIRE | BRIDGESTONE CORPORATION (JP) | 2017-09-28 | — | — | US | disclosed |
| EP-1958980-A1 | THERMOPLASTIC ELASTOMER COMPOSITION, FOAM PRODUCT, AND PROCESS FOR PRODUCTION OF THE COMPOSITION OR FOAM PRODUCT | JSR Corporation (JP) | 2008-08-20 | — | — | EP | disclosed |
| CN-101160328-A | Modified conjugated diene copolymer, rubber compositions and tires | BRIDGESTONE CORP (JP) | 2008-04-09 | — | — | CN | disclosed |
| EP-1873168-A1 | MODIFIED CONJUGATED DIENE COPOLYMER, RUBBER COMPOSITIONS AND TIRES | Bridgestone Corporation (JP) | 2008-01-02 | — | — | EP | disclosed |
| CN-1860169-A | Thermoplastic elastomer composition and molded article | JSR CORP (JP) | 2006-11-08 | — | — | CN | disclosed |
| EP-1026181-B1 | Method of producing conjugated diene polymer | JSR CORP (JP) | 2004-11-24 | — | — | EP | disclosed |
| EP-0957115-B1 | Method for producing conjugated diene polymers | JSR CORP (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-6391990-B1 | Method of producing conjugated diene polymer | JSR CORPORATION (JP) | 2002-05-21 | — | — | US | disclosed |
| US-6255416-B1 | POLYMERIZING CONJUGATED DIENE COMPOUND WITH CATALYST CONSISTING ESSENTIALLY OF COMPOUND CONTAINING RARE EARTH ELEMENT, ALUMOXANE, ORGANOALUMINUM COMPOUND, REACTION PRODUCT OF METAL HALIDE AND LEWIS BASE | JSR CORPORATION (JP) | 2001-07-03 | — | — | US | disclosed |
| EP-1026181-A1 | Method of producing conjugated diene polymer | JSR Corporation (JP) | 2000-08-09 | — | — | EP | disclosed |
| EP-0957115-A1 | Method for producing conjugated diene polymers | JSR Corporation (JP) | 1999-11-17 | — | — | EP | disclosed |