Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 18/20 | 0.51 |
| ▸ | KLK1 | P06870 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6729244 | 0.88 | F10 (0.50) | F10KLK1OPRM1HRH1HRH4 | |
| SCHEMBL6731373 | 0.87 | F10 (0.51) | F10KLK1OPRM1HRH1HRH4 | |
| SCHEMBL6730922 | 0.87 | F10 (0.51) | F10KLK1OPRM1HRH1HRH4 | |
| SCHEMBL6731245 | 0.86 | F10 (0.38) | F10KLK1OPRM1HRH1HRH4 | |
| SCHEMBL6729824 | 0.86 | F10 (0.53) | F10KLK1OPRM1HRH1HRH4 | |
| SCHEMBL6725062 | 0.86 | F10 (0.54) | F10 | |
| SCHEMBL6731239 | 0.85 | HRH4 (0.42) | F10KLK1HRH4HRH3 | |
| SCHEMBL6730764 | 0.84 | F10 (0.56) | F10KLK1OPRM1HRH1HRH4 | |
| SCHEMBL6734184 | 0.83 | F10 (0.64) | F10KLK1 | |
| SCHEMBL6735556 | 0.83 | F10 (0.54) | F10KLK1OPRM1HRH1HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6747023-B1 | INHIBITORS FOR ACTIVATED COAGULATION FACTOR X, COAGULATION SUPPRESSORS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2004-06-08 | — | — | US | disclosed |
| US-20040082611-A1 | Anticoagulants; brain disorders; respiratory system disorders; side effect reduction | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2004-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082611-A1 | Anticoagulants; brain disorders; respiratory system disorders; side effect reduction | F2, CYC1, SULT2A1 | F10 19/4885KLK1 3139/4885OPRM1 910/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.