Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.38 |
| ▸ | FASN | P49327 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 10/20 | 0.38 |
| ▸ | WDR5 | P61964 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3693932 | 0.87 | GHSR (0.42) | OPRM1FASNHTR2A | |
| SCHEMBL3696842 | 0.86 | BRAF (0.41) | FASNHTR2AWDR5 | |
| SCHEMBL3698083 | 0.86 | HTR2A (0.42) | FASNHTR2AWDR5 | |
| SCHEMBL3703934 | 0.85 | HTR2A (0.47) | HTR2A | |
| SCHEMBL3701259 | 0.84 | FASN (0.42) | FASNHTR2A | |
| SCHEMBL3700861 | 0.84 | FASN (0.42) | FASNHTR2A | |
| SCHEMBL3693110 | 0.83 | DYRK1A (0.44) | FASNHTR2A | |
| SCHEMBL3692104 | 0.83 | TP53 (0.45) | FASNHTR2A | |
| SCHEMBL3697727 | 0.83 | HTR2A (0.43) | FASNHTR2A | |
| SCHEMBL6730692 | 0.82 | FASN (0.42) | FASNHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1851199-B1 | SUBSTITUTED BIS ARYL AND HETEROARYL COMPOUNDS AS SELECTIVE 5HT2A ANTAGONISTS | AVENTIS PHARMA INC (US) | 2012-05-16 | — | — | EP | disclosed |