SCHEMBL673284

SCHEMBL673284

CO[PH](=O)Oc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA4 P22748 1/20 0.46
LTA4H P09960 3/20 0.39
TSHR P16473 2/20 0.38
HPGD P15428 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
SRC P12931 1/20 0.33
RAB9A P51151 2/20 0.32
MAPT P10636 1/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
TDP1 Q9NUW8 1/20 0.32
ALOX15 P16050 1/20 0.32
KCNA3 P22001 1/20 0.32
PKM P14618 2/20 0.32
HTT P42858 1/20 0.32
NPC1 O15118 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28946013 0.98 CA4 (0.44) CA4LTA4HTSHRHPGDSMN1; SMN2
SCHEMBL28946021 0.98 CA4 (0.44) CA4LTA4HTSHRHPGDSMN1; SMN2
SCHEMBL28946041 0.98 CA4 (0.44) CA4LTA4HTSHRHPGDSMN1; SMN2
SCHEMBL28946015 0.98 CA4 (0.44) CA4LTA4HTSHRHPGDSMN1; SMN2
Water SCHEMBL7651793 0.98 CA4 (0.44) CA4LTA4HTSHRHPGDSMN1; SMN2
Ethane SCHEMBL11153602 0.85 CA4 (0.43) CA4LTA4HTSHRCA1CA2
SCHEMBL20943 0.85 LTA4H (0.45) CA4LTA4HTSHRCES2CES1
SCHEMBL29790853 0.85 LTA4H (0.45) CA4LTA4HTSHRCES2CES1
Benzene SCHEMBL11134259 0.85 LTA4H (0.45) CA4LTA4HTSHRCES2CES1
SCHEMBL11350262 0.82 LTA4H (0.43) CA4LTA4HTSHRCES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 176 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104662687-B Salts of phosphorus oxide for use as n-type dopants in organic electronic devices 西门子公司 2019-06-14 CN claimed
EP-2758059-B1 SUBSTITUTED PYRIMIDINES MERCK SHARP & DOHME (US) 2018-10-24 EP claimed
CN-104662687-A Salts of phosphorus oxide for use as n-type dopants in organic electronic devices SIEMENS AG 2015-05-27 CN claimed
US-20140349972-A1 SUBSTITUTED PYRIMIDINES MERCK SHARP & DOHME CORP (US) 2014-11-27 US claimed
EP-2758059-A1 SUBSTITUTED PYRIMIDINES Merck Sharp & Dohme Corp. (US) 2014-07-30 EP claimed
CN-101326261-B Organic electroluminescent device MERCK PATENT GMBH 2013-04-24 CN claimed
WO-2013040790-A1 SUBSTITUTED PYRIMIDINES MERCK SHARP & DOHME CORP. (US) 2013-03-28 WO claimed
WO-2013043624-A1 SUBSTITUTED PYRIMIDINES MERCK SHARP & DOHME CORP. (US) 2013-03-28 WO claimed
EP-0736539-B1 Mesoporous crystalline acid composition of a diphosphonate-phosphite of a tetravalent metal which can be used as a catalyst ENITECNOLOGIE SPA (IT) 2000-12-20 EP claimed
US-5892080-A Mesoporous crystalline acid composition of a diphosphonate-phosphite of a tetravalent metal which can be used as a catalyst ENIRICERCHE S.P.A. (IT) 1999-04-06 US claimed
EP-0736539-A2 Mesoporous crystalline acid composition of a diphosphonate-phosphite of a tetravalent metal which can be used as a catalyst ENIRICERCHE S.p.A. (IT) 1996-10-09 EP claimed
US-5272035-A Photosensitive lithographic printing plate having treated aluminum support with diazonium light-sensitive layer containing polyurethane resin and phosphorous additive FUJI PHOTO FILM CO., LTD. (JP) 1993-12-21 US claimed
US-12296304-B2 Membrane for water filtration AQUAPORIN A/S (DK) 2025-05-13 US disclosed
EP-4277731-B1 PROCESS FOR PREPARING A MEMBRANE AQUAPORIN AS (DK) 2024-10-09 EP disclosed
CN-118393811-B Patterning composition, patterning film, patterning substrate, semiconductor device, and method of manufacturing the same 珠海基石科技有限公司 2024-09-03 CN disclosed
CN-118393812-B Patterning composition, patterning film, patterning substrate, semiconductor device, and method of manufacturing the same 珠海基石科技有限公司 2024-08-30 CN disclosed
US-4318783-A Process for the preparation of optionally substituted benzaldehyde dialkyl acetals BAYER AKTIENGESELLSCHAFT (DE) 1982-03-09 US disclosed
US-4255321-A BLENDS WITH HIGH IMPACT-STRENGTH BUTADIENE-STYRENE COPOLYMER INCLUDE A SYNERGISTIC MIXTURE OF A METAL SULFIDE AND ZINC OXIDE; ENGINEERING THERMOPLASTICS GENERAL ELECTRIC COMPANY (US) 1981-03-10 US disclosed
US-4123474-A STABILIZED THERMOPLASTIC MOLDING MATERIAL GENERAL ELECTRIC COMPANY (US) 1978-10-31 US disclosed
US-4076686-A EPOXY ETHANE OR CYCLOHEXANE COMPOUNDS WITH A PHOSPHITE GENERAL ELECTRIC COMPANY (US) 1978-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140349972-A1 SUBSTITUTED PYRIMIDINES HIF1AN, HIF1A, EGLN3 CA4 2265/4885LTA4H 1827/4885TSHR 2794/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.