Sugi Predict

Sugi Predict / Compounds / SCHEMBL673301

SCHEMBL673301

SCHEMBL673301

Nc1c(CC2CO2)cc(Oc2ccccc2)c(CC2CO2)c1CC1CO1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 1/20 0.40
▸ CYP3A4 P08684 2/20 0.36
▸ ALDH1A1 P00352 1/20 0.36
▸ TP53 P04637 1/20 0.36
▸ TSHR P16473 1/20 0.36
▸ SMN1; SMN2 Q16637 1/20 0.36
▸ HIF1A Q16665 1/20 0.36
▸ HRH1 P35367 1/20 0.35
▸ CYP1A2 P05177 1/20 0.34
▸ CYP2C9 P11712 1/20 0.34
▸ CYP2C19 P33261 1/20 0.34
▸ KDM1A O60341 2/20 0.33
▸ DPP4 P27487 1/20 0.33
▸ TAAR1 Q96RJ0 1/20 0.33
▸ ALOX5 P09917 2/20 0.32
▸ MAOB P27338 1/20 0.32
▸ HTR1A P08908 2/20 0.32
▸ ADRA1D P25100 1/20 0.32
▸ ADRA1A P35348 1/20 0.32
▸ SLC6A4 P31645 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28381509 0.81 TDP1 (0.45) TDP1CYP3A4ALDH1A1TP53TSHR
SCHEMBL14353050 0.80 TDP1 (0.44) TDP1CYP3A4ALDH1A1TP53TSHR
SCHEMBL15918926 0.79 TDP1 (0.42) TDP1CYP3A4ALDH1A1TP53TSHR
SCHEMBL14353143 0.78 TDP1 (0.41) TDP1CYP3A4ALDH1A1TP53TSHR
SCHEMBL14352984 0.77 ALDH1A1 (0.41) TDP1CYP3A4ALDH1A1TP53TSHR
SCHEMBL28368473 0.76 TDP1 (0.45) TDP1CYP3A4ALDH1A1TP53TSHR
SCHEMBL14352936 0.73 NCOA1 (0.40) TDP1CYP3A4CYP1A2CYP2C9CYP2C19
SCHEMBL27849237 0.72 CTNNB1 (0.50) TDP1ALDH1A1SMN1; SMN2ALOX5
SCHEMBL11033510 0.71 TDP1 (0.44) TDP1CYP3A4ALDH1A1TP53TSHR
SCHEMBL30587867 0.71 TDP1 (0.46) TDP1CYP3A4ALDH1A1TP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3640275-B1 CURABLE EPOXY COMPOSITIONS AND CURED PRODUCTS THEREOF SHPP GLOBAL TECH BV (NL) 2022-06-29 — — EP claimed
EP-3931238-A1 CROSS-LINKABLE NETWORK FROM FUNCTIONALIZED POLYETHERIMIDE AND THERMOSET POLYMER RESULTING THEREFROM SHPP Global Technologies B.V. (NL) 2022-01-05 — — EP claimed
CN-113710725-A Crosslinkable networks from functionalized polyetherimides and thermoset polymers therefrom 高新特殊工程塑料全球技术有限公司 2021-11-26 — — CN claimed
EP-3640275-A1 CURABLE EPOXY COMPOSITIONS AND CURED PRODUCTS THEREOF SABIC Global Technologies B.V. (NL) 2020-04-22 — — EP claimed
CN-111040130-A Curable high heat epoxy compositions, cured epoxy compositions thereof, methods of manufacture thereof, and articles comprising the same 沙特基础工业全球技术有限公司 2020-04-21 — — CN claimed
US-20200115544-A1 CURABLE EPOXY COMPOSITIONS AND CURED PRODUCTS THEREOF SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2020-04-16 — — US claimed
US-20220145065-A1 CROSS-LINKABLE NETWORK FROM FUNCTIONALIZED POLYETHERIMIDE AND THERMOSET POLYMER RESULTING THEREFROM SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2022-05-12 — — US disclosed
EP-3931238-A1 CROSS-LINKABLE NETWORK FROM FUNCTIONALIZED POLYETHERIMIDE AND THERMOSET POLYMER RESULTING THEREFROM SHPP Global Technologies B.V. (NL) 2022-01-05 — — EP disclosed
CN-113710725-A Crosslinkable networks from functionalized polyetherimides and thermoset polymers therefrom 高新特殊工程塑料全球技术有限公司 2021-11-26 — — CN disclosed
WO-2021096654-A1 CURING COMPOSITION FOR HIGH HEAT ADHESIVE EPOXY RESIN SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2021-05-20 — — WO disclosed
EP-3504283-B1 SOLID HOMOGENEOUS AMORPHOUS HIGH HEAT EPOXY BLENDS, ARTICLES, AND USES THEREOF SHPP GLOBAL TECH BV (NL) 2021-04-07 — — EP disclosed
US-10870724-B2 High heat monomers and methods of use thereof SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2020-12-22 — — US disclosed
US-20200263052-A1 SOLID HOMOGENEOUS AMORPHOUS HIGH HEAT EPOXY BLENDS, ARTICLES, AND USES THEREOF SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2020-08-20 — — US disclosed
US-5624979-A Stabilized phosphorus-modified epoxy resins and their use HOECHST AKTIENGESELLSCHAFT (DE) 1997-04-29 — — US disclosed
EP-0735119-A1 Flame-retardant coating composition HOECHST AKTIENGESELLSCHAFT (DE) 1996-10-02 — — EP disclosed
EP-0719825-A2 Phosphorus-modified stabilized epoxy resins and their use HOECHST AKTIENGESELLSCHAFT (DE) 1996-07-03 — — EP disclosed
EP-0689558-A1 PHOSPHORUS-MODIFIED EPOXY RESINS, PROCESS FOR PRODUCING THEM AND THEIR USE SIEMENS AKTIENGESELLSCHAFT (DE) 1996-01-03 — — EP disclosed
EP-0689560-A1 PHOSPHORUS-MODIFIED EPOXY RESINS, PROCESS FOR PRODUCING THEM AND THEIR USE SIEMENS AKTIENGESELLSCHAFT (DE) 1996-01-03 — — EP disclosed
WO-1994021704-A1 PHOSPHORUS-MODIFIED EPOXY RESINS, PROCESS FOR PRODUCING THEM AND THEIR USE SIEMENS AKTIENGESELLSCHAFT (DE) 1994-09-29 — — WO disclosed
WO-1994021705-A1 PHOSPHORUS-MODIFIED EPOXY RESINS, PROCESS FOR PRODUCING THEM AND THEIR USE SIEMENS AKTIENGESELLSCHAFT (DE) 1994-09-29 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10870724-B2 High heat monomers and methods of use thereof HSP90AA1, HSP90AB1, EPHX2 TDP1 1875/4885CYP3A4 511/4885ALDH1A1 318/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.