Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.33 |
| ▸ | WEE1 | P30291 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.32 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | CASR | P41180 | 1/20 | 0.30 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.30 |
| ▸ | MYLK | Q15746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6231131 | 0.95 | CYP2C9 (0.54) | CYP2C9MAPK1HSD17B10NR1I2CHEK1 | |
| SCHEMBL6738002 | 0.91 | CYP2C9 (0.62) | CYP2C9MAPK1HSD17B10NR1I2 | |
| SCHEMBL6233730 | 0.91 | CYP2C9 (0.53) | CYP2C9MAPK1HSD17B10NR1I2 | |
| SCHEMBL6207951 | 0.90 | MAPK1 (0.58) | CYP2C9MAPK1HSD17B10NR1I2ALDH1A1 | |
| SCHEMBL6232672 | 0.89 | CYP2C9 (0.51) | CYP2C9MAPK1HSD17B10NR1I2 | |
| SCHEMBL6732252 | 0.88 | CYP2C9 (0.65) | CYP2C9MAPK1HSD17B10NR1I2CHEK1 | |
| SCHEMBL6735217 | 0.87 | CYP2C9 (0.51) | CYP2C9MAPK1HSD17B10NR1I2 | |
| SCHEMBL6233801 | 0.86 | MAPK1 (0.53) | CYP2C9MAPK1HSD17B10NR1I2CHEK1 | |
| SCHEMBL1522950 | 0.84 | MAPK1 (0.47) | CYP2C9MAPK1HSD17B10NR1I2THRB | |
| SCHEMBL6233871 | 0.83 | MAPK1 (0.66) | CYP2C9MAPK1HSD17B10NR1I2CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040147739-A1 | Novel anti-infectives | SMITHKLINE BEECHAM CORPORATION | 2004-07-29 | — | — | US | claimed |
| US-20040147739-A1 | Novel anti-infectives | SMITHKLINE BEECHAM CORPORATION | 2004-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040147739-A1 | Novel anti-infectives | RPL5, RPL7, RPL35 | CYP2C9 1218/4885MAPK1 3699/4885HSD17B10 1428/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.