RPL7

Large ribosomal subunit protein uL30 · P18124 · RPL7 on Sugi Atlas →

3,677 patent compounds predicted against RPL7, 1,927 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL5500526 SCHEMBL5500526 0.41 4/20
SCHEMBL5500532 SCHEMBL5500532 0.41 4/20
SCHEMBL5503310 SCHEMBL5503310 0.41 4/20
SCHEMBL11844361 SCHEMBL11844361 0.35 4/20
SCHEMBL2000440 SCHEMBL2000440 0.39 3/20
SCHEMBL8219903 SCHEMBL8219903 0.36 3/20
SCHEMBL11627320 SCHEMBL11627320 0.34 3/20
SCHEMBL10271044 SCHEMBL10271044 0.55 2/20
SCHEMBL6394396 SCHEMBL6394396 0.47 2/20
N-Methylpiperidine N-Methylpiperidine (SCHEMBL11205373) 0.42 2/20
Bicarbonate Bicarbonate (SCHEMBL9058396) 0.42 2/20
SCHEMBL4960293 SCHEMBL4960293 0.41 2/20
SCHEMBL4961968 SCHEMBL4961968 0.40 2/20
SCHEMBL6686992 SCHEMBL6686992 0.40 2/20
SCHEMBL9429122 SCHEMBL9429122 0.38 2/20
Chloramphenicol Chloramphenicol (SCHEMBL10796001) 1.00 1/20
Geneticin Geneticin (SCHEMBL15596) 0.93 1/20
Geneticin Geneticin (SCHEMBL5006573) 0.93 1/20
Geneticin Geneticin (SCHEMBL9920496) 0.93 1/20
Chloramphenicol Chloramphenicol (SCHEMBL16111) 0.90 1/20

Clinical trials — most relevant to RPL7 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Effects of Liraglutide on ER Stress in Obese Patients With Type 2 Diabetes PHASE4UNKNOWN
Antiviral Activity and Safety of 3 Different Doses of Mifepristone in Hepatitis C Infected Patients PHASE2COMPLETED
Sirolimus in Combination With Metronomic Chemotherapy in Children With High-Risk Solid Tumors PHASE2RECRUITING
Targeting Endoplasmic Reticulum Stress in Human Hypertension PHASE1/PHASE2RECRUITING
Study of Decitabine in Combination With Sequential Rapamycin or Ribavirin in High Risk AML Patients PHASE1/PHASE2COMPLETED
Everolimus for Children With Recurrent or Progressive Ependymoma PHASE2COMPLETED
Reverse Transcriptase Inhibitors in AGS PHASE2COMPLETED
EBV Lytic Reactivation Therapy Combined With PD-1 Antibody in Recurrent/Metastatic Nasopharyngeal Carcinoma PHASE2NOT_YET_RECRUITING
Temsirolimus and Sorafenib in Advanced Hepatocellular Carcinoma PHASE1COMPLETED
Study of Oral CNF2024 (BIIB021) in Advanced Solid Tumors PHASE1COMPLETED
Safety and Pharmacology of SNX-5422 Plus Carboplatin and Paclitaxel in Subjects With Solid Tumors PHASE1COMPLETED
Phase I Safety and Immunogenicity Preventative Vaccine Trial Based on Recombinant Tat Protein PHASE1COMPLETED
PS-341 and Radiation to Treat Advanced Cancer of the Head and Neck PHASE1COMPLETED
Evaluation of the Safety and Tolerability of i.v. Administration of a Cancer Vaccine in Patients With Advanced Melanoma PHASE1COMPLETED
Clinical Study of Therapeutic Immunological Agent for EBV-positive Advanced Malignant Tumors PHASE1ACTIVE_NOT_RECRUITING
17-N-Allylamino-17-Demethoxygeldanamycin in Treating Patients With Solid Tumors That Cannot Be Removed By Surgery PHASE1COMPLETED
Human Leukocyte Antigen (HLA) - A*2402 Restricted Peptide Vaccine Therapy in Patients With Advanced Gastric Cancer PHASE1COMPLETED
Micro Ribosomal Nucleic Acid 155 in Non Hodgkin Lymphoma nanCOMPLETED
Differential Gene Expression of Liver Tissue and Blood From Individuals With Chronic Viral Hepatitis nanUNKNOWN
Cytomegalovirus (CMV) MicroRNA Expression in Vivo and Immune Evasion Correlates nanCOMPLETED
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Pharmacogenomics of Interferon and Ribavirin Treatment in Patients With Chronic Hepatitis C Virus Infection nanUNKNOWN
Pilot Trial of Sirolimus/MEC in High Risk Acute Myelogenous Leukemia (AML) nanCOMPLETED
Effect of Branched Chain Amino Acids on Muscle nanCOMPLETED
Quantification of GADD34 Expression in RA nanCOMPLETED
Regulation of Lymphocyte Anti-tumor Response in Metastatic Patients Treated With the mTOR Inhibitor Everolimus nanCOMPLETED
The Efficiency of Postoperative Interferon-alpha Treatment in p48 Positive Patients With Hepatocellular Carcinoma nanWITHDRAWN
Maximizing Mechanisms of Muscle Hypertrophy to Combat Sarcopenia in Older Adults nanCOMPLETED
Valproic Acid-associated Hypoalbuminemia in Medically Fragile Patients nanCOMPLETED
Exercise-induced Epigenetic Adaptations nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a RPL7 binder may also engage these)

ProteinNameSimilarity
Q5R9R4 1.000 Q5R9R4 →
Q58DT1 1.000 Q58DT1 →
Q5ZJ56 0.999 Q5ZJ56 →
Q4R506 0.998 Q4R506 →
P14148 0.995 P14148 →
P05426 0.994 P05426 →
G1SV32 0.992 G1SV32 →
Q7SBD5 0.990 Q7SBD5 →
Q6C603 0.990 Q6C603 →
P05737 0.988 P05737 →
Q9LHP1 0.987 Q9LHP1 →
P32100 0.987 P32100 →
P60039 0.987 P60039 →
P11874 0.986 P11874 →
O01802 0.986 O01802 →
P60040 0.985 P60040 →
Q5RAH8 0.984 Q5RAH8 →
Q12213 0.984 Q12213 →
Q6FSN6 0.983 Q6FSN6 →
A0CEY2 0.983 A0CEY2 →
P17937 0.981 P17937 →
O60143 0.981 O60143 →
Q6DKI1 0.981 Q6DKI1 →
Q9D8M4 0.981 Q9D8M4 →
A0BD73 0.980 A0BD73 →
A0A1D8PDL6 0.980 A0A1D8PDL6 →
A5GFQ0 0.980 A5GFQ0 →
Q6BTA4 0.980 Q6BTA4 →
Q755A7 0.979 Q755A7 →
P25457 0.977 P25457 →