Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.54 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.51 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | WEE1 | P30291 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | TEK | Q02763 | 1/20 | 0.32 |
| ▸ | PLK1 | P53350 | 1/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL6686682 | 0.95 | MAPK1 (0.52) | MAPK1HSD17B10CYP2C9NR1I2CHEK1 | |
| SCHEMBL6231418 | 0.94 | CYP2C9 (0.62) | MAPK1HSD17B10CYP2C9NR1I2CHEK1 | |
| SCHEMBL6231207 | 0.93 | MAPK1 (0.66) | MAPK1HSD17B10CYP2C9NR1I2CHEK1 | |
| SCHEMBL6236792 | 0.93 | MAPK1 (0.66) | MAPK1HSD17B10CYP2C9NR1I2MEN1 | |
| SCHEMBL6235865 | 0.93 | CYP2C9 (0.53) | MAPK1HSD17B10CYP2C9NR1I2CHEK1 | |
| SCHEMBL6732912 | 0.89 | MAPK1 (0.57) | MAPK1HSD17B10CYP2C9NR1I2CHEK1 | |
| SCHEMBL6233730 | 0.88 | CYP2C9 (0.53) | MAPK1HSD17B10CYP2C9NR1I2CNR2 | |
| SCHEMBL1522562 | 0.85 | MAPK1 (0.51) | MAPK1HSD17B10CYP2C9NR1I2ALDH1A1 | |
| SCHEMBL6233801 | 0.85 | MAPK1 (0.53) | MAPK1HSD17B10CYP2C9NR1I2CHEK1 | |
| SCHEMBL6732332 | 0.85 | CYP2C9 (0.61) | MAPK1HSD17B10CYP2C9NR1I2CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1535151-A | Novel anti-infectives | ʷ��˿�������ȳ�ķ����˾ | 2004-10-06 | — | — | CN | claimed |
| US-20040147739-A1 | Novel anti-infectives | SMITHKLINE BEECHAM CORPORATION | 2004-07-29 | — | — | US | claimed |
| US-20040147739-A1 | Novel anti-infectives | SMITHKLINE BEECHAM CORPORATION | 2004-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040147739-A1 | Novel anti-infectives | RPL5, RPL7, RPL35 | MAPK1 3699/4885HSD17B10 1428/4885CYP2C9 1218/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.