SCHEMBL673329

SCHEMBL673329

Cc1cc(C2(c3ccc(O)c(C)c3)CCC(c3ccc(O)c(C)c3)(c3ccc(O)c(C)c3)CC2)ccc1O

nearest known ligand 0.85

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 11/20 0.85
ESR2 Q92731 9/20 0.85
ACHE P22303 1/20 0.48
TDP1 Q9NUW8 2/20 0.48
TP53 P04637 1/20 0.48
PDE10A Q9Y233 1/20 0.45
LMNA P02545 4/20 0.42
MAPT P10636 3/20 0.42
NPSR1 Q6W5P4 3/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
XBP1 P17861 1/20 0.42
POLB P06746 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
ALOX12 P18054 3/20 0.41
AR P10275 3/20 0.41
KDM4E B2RXH2 1/20 0.39
ALDH1A1 P00352 1/20 0.39
CYP1A2 P05177 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14667785 0.92 ESR1 (0.73) ESR1ESR2ACHETDP1TP53
SCHEMBL464980 0.92 ESR1 (1.00) ESR1ESR2ACHETDP1TP53
SCHEMBL29763085 0.92 ESR1 (1.00) ESR1ESR2ACHETDP1TP53
SCHEMBL19863505 0.92 ESR1 (0.92) ESR1ESR2ACHETDP1TP53
SCHEMBL673869 0.90 ESR1 (1.00) ESR1ESR2ACHETDP1TP53
SCHEMBL675104 0.90 ESR1 (1.00) ESR1ESR2ACHETDP1TP53
SCHEMBL74159 0.90 ESR1 (1.00) ESR1ESR2ACHETDP1TP53
SCHEMBL673904 0.90 ESR1 (1.00) ESR1ESR2ACHETDP1TP53
SCHEMBL464963 0.90 ESR1 (1.00) ESR1ESR2ACHETDP1TP53
SCHEMBL10776828 0.90 ESR1 (1.00) ESR1ESR2ACHETDP1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070106051-A1 Polyfunctional poly(arylene ether) method CITIBANK, N.A., AS COLLATERAL AGENT 2007-05-10 US claimed
US-4277600-A Tetraphenolic compounds and polycarbonates containing the same GENERAL ELECTRIC COMPANY (US) 1981-07-07 US claimed
EP-2867275-B1 POLY(PHENYLENE ETHER) PROCESS SABIC GLOBAL TECHNOLOGIES BV (NL) 2017-11-22 EP disclosed
US-9563121-B2 Actinic ray-sensitive or radiation-sensitive resin composition, and, actinic ray-sensitive or radiation-sensitive film and pattern forming method, each using the composition FUJIFILM CORPORATION (JP) 2017-02-07 US disclosed
US-9563121-B2 Actinic ray-sensitive or radiation-sensitive resin composition, and, actinic ray-sensitive or radiation-sensitive film and pattern forming method, each using the composition FUJIFILM CORPORATION (JP) 2017-02-07 US disclosed
US-9235116-B2 Actinic-ray- or radiation sensitive resin composition, actinic-ray- or radiation-sensitive film therefrom and method of forming pattern FUJIFILM CORPORATION (JP) 2016-01-12 US disclosed
US-9235116-B2 Actinic-ray- or radiation sensitive resin composition, actinic-ray- or radiation-sensitive film therefrom and method of forming pattern FUJIFILM CORPORATION (JP) 2016-01-12 US disclosed
US-20140342275-A1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, AND, ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE FILM AND PATTERN FORMING METHOD, EACH USING THE COMPOSITION FUJIFILM CORPORATION (JP) 2014-11-20 US disclosed
US-8734693-B2 Method of separating a poly(arylene ether) composition from a solvent, and poly(arylene ether) composition prepared thereby SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2014-05-27 US disclosed
US-8673538-B2 Actinic ray-sensitive or radiation-sensitive resin composition, and actinic ray-sensitive or radiation-sensitive film and pattern forming method using the composition FUJIFILM CORPORATION (JP) 2014-03-18 US disclosed
US-8574814-B2 Actinic ray-sensitive or radiation-sensitive resin composition, and actinic ray-sensitive or radiation-sensitive film and pattern forming method using the composition FUJIFILM CORPORATION (JP) 2013-11-05 US disclosed
US-20080097069-A1 POLY(ARYLENE ETHER) METHOD AND COMPOSITION CITIBANK, N.A., AS COLLATERAL AGENT 2008-04-24 US disclosed
US-7321054-B2 Method of producing poly(ortho-methylphenol) HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2008-01-22 US disclosed
US-20070224540-A1 Positive resist composition and pattern formation method using the same FUJIFILM CORPORATION (JP) 2007-09-27 US disclosed
US-20070224540-A1 Positive resist composition and pattern formation method using the same FUJIFILM CORPORATION (JP) 2007-09-27 US disclosed
US-20070197832-A1 METHOD OF PRODUCING POLY(ORTHO-METHYLPHENOL) HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2007-08-23 US disclosed
US-20070106051-A1 Polyfunctional poly(arylene ether) method CITIBANK, N.A., AS COLLATERAL AGENT 2007-05-10 US disclosed
US-20070072117-A1 Positive resist composition and pattern forming method using the same FUJI PHOTO FILM CO., LTD. 2007-03-29 US disclosed
US-20070072117-A1 Positive resist composition and pattern forming method using the same FUJI PHOTO FILM CO., LTD. 2007-03-29 US disclosed
US-5856058-A HALATION INHIBITOR WHICH IS AN ESTERIFICATION PRODUCT BETWEEN A SPECIFIED PHENOLIC COMPOUND AND A NAPHTHOQUINONE-1,2-DIAZIDE SULFONIC ACID. TOKYO OHKA KOGYO CO., LTD. (JP) 1999-01-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070197832-A1 METHOD OF PRODUCING POLY(ORTHO-METHYLPHENOL) COMT, HPD, KDM8 ESR1 871/4885ESR2 1813/4885ACHE 201/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.