SCHEMBL6733546

SCHEMBL6733546

Cc1cc[n+]([O-])c(-c2ccc(C(=O)N3CCN(S(=O)(=O)c4nc5ccc(Cl)cc5[nH]4)CC3)cc2)c1

nearest known ligand 0.49

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
F10 P00742 11/20 0.49
KLK1 P06870 1/20 0.47
HRH4 Q9H3N8 4/20 0.44
HRH3 Q9Y5N1 1/20 0.44
TDP1 Q9NUW8 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
ALOX15 P16050 1/20 0.41
ATR Q13535 1/20 0.40
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6733552 0.94 F10 (0.49) F10KLK1TDP1L3MBTL1MEN1
SCHEMBL6728895 0.90 HRH4 (0.44) F10KLK1HRH4HRH3TDP1
SCHEMBL6730036 0.89 HRH4 (0.43) F10KLK1HRH4HRH3TDP1
SCHEMBL6725004 0.89 F10 (0.48) F10KLK1HRH4HRH3L3MBTL1
SCHEMBL6733159 0.88 F10 (0.49) F10KLK1HRH4HRH3TDP1
SCHEMBL6731719 0.86 F10 (0.49) F10KLK1HRH4HRH3TDP1
SCHEMBL6728397 0.85 F10 (0.47) F10KLK1HRH4HRH3TDP1
SCHEMBL6726164 0.84 F10 (0.47) F10KLK1HRH4HRH3ALOX15
SCHEMBL6730046 0.83 F10 (0.49) F10KLK1HRH4HRH3TDP1
SCHEMBL6728982 0.83 F10 (0.46) F10KLK1HRH4HRH3ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6747023-B1 INHIBITORS FOR ACTIVATED COAGULATION FACTOR X, COAGULATION SUPPRESSORS DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2004-06-08 US disclosed
US-20040082611-A1 Anticoagulants; brain disorders; respiratory system disorders; side effect reduction DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2004-04-29 US disclosed
EP-1104754-A1 NOVEL SULFONYL DERIVATIVES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2001-06-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040082611-A1 Anticoagulants; brain disorders; respiratory system disorders; side effect reduction F2, CYC1, SULT2A1 F10 19/4885KLK1 3139/4885HRH4 506/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.