SCHEMBL6733771

SCHEMBL6733771

CCOC(=O)CC1CN(S(=O)(=O)n2cc3ccc(C(N)=NO)cc3c2)CCN1C(=O)c1nc2c(s1)CNC(C)C2

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
F10 P00742 6/20 0.35
ITGB3 P05106 2/20 0.32
ITGA2B P08514 2/20 0.32
F2 P00734 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6733767 1.00 F10 (0.35) F10ITGB3ITGA2BF2
SCHEMBL6725050 0.94 F10 (0.33) F10F2
SCHEMBL6725056 0.94 F10 (0.33) F10F2
SCHEMBL6726523 0.92 F10 (0.36) F10ITGB3ITGA2BF2
SCHEMBL6737788 0.92 F10 (0.37) F10F2
SCHEMBL6737791 0.92 F10 (0.37) F10F2
SCHEMBL6735502 0.91 F10 (0.39) F10F2
SCHEMBL6735504 0.91 F10 (0.39) F10F2
SCHEMBL6736931 0.90 F10 (0.36) F10F2
SCHEMBL6736927 0.90 F10 (0.36) F10F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040082611-A1 Anticoagulants; brain disorders; respiratory system disorders; side effect reduction DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2004-04-29 US disclosed
EP-1104754-A1 NOVEL SULFONYL DERIVATIVES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2001-06-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040082611-A1 Anticoagulants; brain disorders; respiratory system disorders; side effect reduction F2, CYC1, SULT2A1 F10 19/4885ITGB3 1072/4885ITGA2B 800/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.