Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 7/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 2/20 | 0.37 |
| ▸ | HTR3A | P46098 | 2/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6738470 | 0.86 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1LMNASMN1; SMN2HTT | |
| SCHEMBL6740425 | 0.81 | ALDH1A1 (0.58) | ALDH1A1L3MBTL1LMNASMN1; SMN2HTT | |
| SCHEMBL6738120 | 0.80 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1LMNASMN1; SMN2HTT | |
| SCHEMBL6735158 | 0.80 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1LMNASMN1; SMN2HTT | |
| SCHEMBL6733748 | 0.79 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1LMNASMN1; SMN2HTT | |
| SCHEMBL6737762 | 0.79 | ALDH1A1 (0.60) | ALDH1A1L3MBTL1LMNASMN1; SMN2HTT | |
| SCHEMBL6740943 | 0.78 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1LMNASMN1; SMN2HTT | |
| SCHEMBL6740952 | 0.78 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1LMNASMN1; SMN2HTT | |
| SCHEMBL6740194 | 0.77 | ALDH1A1 (0.60) | ALDH1A1L3MBTL1LMNASMN1; SMN2HTT | |
| SCHEMBL6739641 | 0.77 | ALDH1A1 (0.60) | ALDH1A1L3MBTL1LMNASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6686357-B1 | BENZIMIDAZOLO-PIPERIDINE COMPOUND | PFIZER, INC. | 2004-02-03 | — | — | US | disclosed |