SCHEMBL6733972

SCHEMBL6733972

CCCCNCCCNCCC

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.65
ALDH1A1 P00352 1/20 0.65
CYP2C19 P33261 2/20 0.56
MEN1 O00255 1/20 0.56
GLA P06280 1/20 0.56
KMT2A Q03164 1/20 0.56
CYP1A2 P05177 1/20 0.53
PAOX Q6QHF9 1/20 0.48
ADH1B P00325 1/20 0.46
ADH1C P00326 1/20 0.46
ADH1A P07327 1/20 0.46
ADH7 P40394 1/20 0.46
CA12 O43570 2/20 0.42
CA2 P00918 2/20 0.42
CA7 P43166 2/20 0.42
CA14 Q9ULX7 2/20 0.42
CA3 P07451 1/20 0.42
CA4 P22748 1/20 0.42
CA6 P23280 1/20 0.42
CA5A P35218 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5701105 1.00 TSHR (0.65) TSHRALDH1A1CYP2C19MEN1GLA
SCHEMBL5701157 1.00 TSHR (0.65) TSHRALDH1A1CYP2C19MEN1GLA
SCHEMBL74704 0.97
SCHEMBL1685473 0.97 TSHR (0.69) TSHRALDH1A1CYP2C19MEN1GLA
SCHEMBL18427255 0.93 TSHR (0.65) TSHRALDH1A1CYP2C19MEN1GLA
Ammonia Solution, Strong SCHEMBL11331652 0.93
Hydrochloric Acid SCHEMBL22771814 0.93
SCHEMBL2856763 0.93 TSHR (0.65) TSHRALDH1A1CYP2C19MEN1GLA
SCHEMBL2905152 0.93 CYP2C19 (0.62) TSHRALDH1A1CYP2C19MEN1GLA
SCHEMBL1276412 0.93 CYP2C19 (0.62) TSHRALDH1A1CYP2C19MEN1GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1370563-A1 MESOPOROUS ORGANIC-INORGANIC HYBRID MATERIALS FOR SEPARATING GASES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2003-12-17 EP claimed
WO-2002076991-A1 MESOPOROUS ORGANIC-INORGANIC HYBRID MATERIALS FOR SEPARATING GASES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2002-10-03 WO claimed
US-8182695-B2 Bridged macrocyclic module compositions WHITEFORD JEFFERY A (US) 2012-05-22 US disclosed
US-20080290034-A1 Bridged macrocyclic module compositions COVALENT PARTNERS LLC 2008-11-27 US disclosed
US-7368564-B2 Bridged macrocyclic module compositions COVALENT PARTNERS, LLC (US) 2008-05-06 US disclosed
EP-1370563-A1 MESOPOROUS ORGANIC-INORGANIC HYBRID MATERIALS FOR SEPARATING GASES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2003-12-17 EP disclosed
WO-2002076991-A1 MESOPOROUS ORGANIC-INORGANIC HYBRID MATERIALS FOR SEPARATING GASES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2002-10-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080290034-A1 Bridged macrocyclic module compositions SBDS, NCL, INTS6 TSHR 4746/4885ALDH1A1 3961/4885CYP2C19 1107/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.