SBDS

Ribosome maturation protein SBDS · Q9Y3A5 · SBDS on Sugi Atlas →

0 patent compounds predicted against SBDS, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to SBDS by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Methylphenidate in KBG Syndrome: N-of-1 Series PHASE4RECRUITING
Betaine and Peroxisome Biogenesis Disorders PHASE3COMPLETED
Study of the Selective GlyT1 Inhibitor Bitopertin for Steroid-Refractory Diamond-Blackfan Anemia PHASE1/PHASE2COMPLETED
BI-1910 as a Single Agent and in Combination With Pembrolizumab for the Treatment of Advanced Solid Tumors PHASE1/PHASE2ACTIVE_NOT_RECRUITING
Mobilization of Stem Cells With G-CSF for Collection From Patients With Diamond-Blackfan Anemia PHASE2COMPLETED
Tianasen (ASO-GNAO1) for GNAO1-Encephalopathy With Epilepsy and Movement Disorders. PHASE1/PHASE2RECRUITING
Antiviral Activity and Safety of 3 Different Doses of Mifepristone in Hepatitis C Infected Patients PHASE2COMPLETED
A Phase 1/2, First-in-Human Dose Escalation/Expansion Study to Evaluate the Safety, Tolerability and Preliminary Efficacy of a Subretinal Injection of SB-007 in Subjects With Stargardt Disease (STGD1) PHASE1/PHASE2RECRUITING
Assessing the Safety, Tolerability, and Efficacy of APR-2020 in Pediatric and Adolescent Subjects With RPS19 Deficient Diamond-Blackfan Anemia PHASE1RECRUITING
Telomere Repair Gene Mutation in Inflammatory Bowel Disease nanCOMPLETED
Mobilization of CD34+ Peripheral Blood Stem Cells in Patients With Diamond Blackfan Anemia Syndrome (DBAS) nanRECRUITING
Shwachman Diamond Syndrome Registry and Study nanRECRUITING
Bone Manifestation of Nutritional Disorders Among Infants and Pre-school Children nanUNKNOWN
Mechanisms of Inherited Retinal Dystrophies Using Whole Genome Sequencing and in Vitro and in Vivo Models nanCOMPLETED
The Effects of Whey vs. Collagen on MPS nanCOMPLETED
The Effect of Dairy and Dairy-Free Alternative Beverages on Post-Exercise Anabolism in Active Youth nanUNKNOWN
Effect of Branched Chain Amino Acids on Muscle nanCOMPLETED
A Multicentric European Study to Promote Clinical Trial Readiness for STXBP1-related Disorders nanRECRUITING
Establishment of Human Cellular Disease Models for Wilson Disease nanCOMPLETED
Diagnosis of RSTS: Identification of the Acetylation Profiles as Epigenetic Markers for Assessing Causality of CREBBP and EP300 Variants. nanUNKNOWN
Role of SF3B1 Mutation in Assessment of Acute and Chronic Lymphatic Leukemia nanNOT_YET_RECRUITING
Natural History Study of Inherited Retinal Diseases nanRECRUITING
Nephrotic Syndrome Study Network nanRECRUITING
MicroRNA-1 (miRNA-1) and MicroRNA-133a (miRNA-133a) Levels After Acute Exercise in Ultimate Frisbee Athletes nanUNKNOWN
Detection of Pompe Disease in Adult Patients With Myopathies of Uncertain Origin or With Asymptomatic Hyper-CK-emia nanUNKNOWN
Diffuse Cutaneous Scleroderma (DSSc) SFDI Study nanRECRUITING
Pathogenesis of Primary Ciliary Dyskinesia (PCD) Lung Disease nanRECRUITING
Muscle Regrowth During Physical Rehabilitation and Amino Acid Supplementation nanCOMPLETED
European Registry on Rare Neurological Diseases nanUNKNOWN
Maximizing Mechanisms of Muscle Hypertrophy to Combat Sarcopenia in Older Adults nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a SBDS binder may also engage these)

ProteinNameSimilarity
Q5RAZ2 1.000 Q5RAZ2 →
Q3SWZ6 1.000 Q3SWZ6 →
Q5RK30 1.000 Q5RK30 →
P70122 1.000 P70122 →
A5D8M6 1.000 A5D8M6 →
Q5ZIY4 0.997 Q5ZIY4 →
Q6DIT8 0.993 Q6DIT8 →
O14179 0.990 O14179 →
Q23202 0.986 Q23202 →
Q86KZ5 0.982 Q86KZ5 →
P42942 0.978 P42942 →
Q59P53 0.978 Q59P53 →
Q64511 0.977 Q64511 →
Q9FLE4 0.977 Q9FLE4 →
Q757H7 0.977 Q757H7 →
P46943 0.977 P46943 →
Q9ZT87 0.976 Q9ZT87 →
Q23670 0.976 Q23670 →
O42130 0.975 O42130 →
O42131 0.975 O42131 →
A1D5Z0 0.975 A1D5Z0 →
C5JRK2 0.975 C5JRK2 →
Q7ZWC4 0.975 Q7ZWC4 →
Q6CUH2 0.975 Q6CUH2 →
P21894 0.975 P21894 →
TOP2B DNA topoisomerase 2-beta 0.974 landscape →
C4YIT6 0.974 C4YIT6 →
Q64399 0.974 Q64399 →
C7ZA26 0.974 C7ZA26 →
Q84WV1 0.974 Q84WV1 →