SCHEMBL6734091

SCHEMBL6734091

Cc1ccnc(-c2ccc(C(=O)N3CCN(S(=O)(=O)c4ccc5cc(Cl)ccc5c4)CC3)cc2)c1

nearest known ligand 0.57

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
F10 P00742 11/20 0.57
ATM Q13315 1/20 0.55
ABL1 P00519 4/20 0.54
BCR P11274 4/20 0.54
SMN1; SMN2 Q16637 1/20 0.52
F2 P00734 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6730863 0.89 F10 (0.54) F10ATMSMN1; SMN2F2
SCHEMBL6730925 0.88 F10 (0.50) F10ATMSMN1; SMN2F2
SCHEMBL6195355 0.88 ATM (0.61) F10ATMABL1BCRSMN1; SMN2
Hydrochloric Acid SCHEMBL6198123 0.87 ATM (0.60) F10ATMABL1BCRSMN1; SMN2
SCHEMBL6195975 0.87 F10 (0.57) F10ATMSMN1; SMN2F2
SCHEMBL5736203 0.86 ATM (0.54) F10ATMSMN1; SMN2F2
Hydrochloric Acid SCHEMBL6195328 0.86 F10 (0.56) F10ATMSMN1; SMN2F2
SCHEMBL6389239 0.85 ATM (0.60) F10ATMSMN1; SMN2F2
SCHEMBL5193868 0.84 ATM (0.71) F10ATMSMN1; SMN2F2
Hydrochloric Acid SCHEMBL6202035 0.84 F10 (0.56) F10ATMSMN1; SMN2F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6747023-B1 INHIBITORS FOR ACTIVATED COAGULATION FACTOR X, COAGULATION SUPPRESSORS DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2004-06-08 US disclosed
US-20040082611-A1 Anticoagulants; brain disorders; respiratory system disorders; side effect reduction DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2004-04-29 US disclosed
EP-1104754-A1 NOVEL SULFONYL DERIVATIVES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2001-06-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040082611-A1 Anticoagulants; brain disorders; respiratory system disorders; side effect reduction F2, CYC1, SULT2A1 F10 19/4885ATM 2080/4885ABL1 2357/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.