Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 3/20 | 0.59 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.59 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.59 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | MMP2 | P08253 | 2/20 | 0.53 |
| ▸ | ALPI | P09923 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | XIAP | P98170 | 1/20 | 0.53 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.53 |
| ▸ | MMP1 | P03956 | 1/20 | 0.53 |
| ▸ | MMP9 | P14780 | 1/20 | 0.53 |
| ▸ | MMP8 | P22894 | 1/20 | 0.53 |
| ▸ | MMP13 | P45452 | 1/20 | 0.53 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6734115 | 1.00 | SLC1A3 (0.59) | SLC1A3SLC1A2SLC1A1CA1CA2 | |
| Hydrochloric Acid SCHEMBL7461056 | 0.98 | SLC1A3 (0.57) | SLC1A3SLC1A2SLC1A1CA1CA2 | |
| Hydrochloric Acid SCHEMBL7461064 | 0.98 | SLC1A3 (0.57) | SLC1A3SLC1A2SLC1A1CA1CA2 | |
| SCHEMBL13585555 | 0.81 | CA12 (0.62) | SLC1A3SLC1A2SLC1A1CA1CA2 | |
| SCHEMBL13585561 | 0.81 | CA12 (0.62) | SLC1A3SLC1A2SLC1A1CA1CA2 | |
| SCHEMBL457773 | 0.80 | SLC1A3 (0.52) | SLC1A3SLC1A2SLC1A1CA1CA2 | |
| SCHEMBL383078 | 0.78 | GBA1 (0.63) | SLC1A3SLC1A2SLC1A1CA2MMP2 | |
| SCHEMBL1768682 | 0.78 | GBA1 (0.63) | SLC1A3SLC1A2SLC1A1CA2MMP2 | |
| Hydrochloric Acid SCHEMBL382132 | 0.77 | GBA1 (0.61) | SLC1A3SLC1A2SLC1A1CA2MMP2 | |
| Hydrochloric Acid SCHEMBL7662277 | 0.77 | GBA1 (0.61) | SLC1A3SLC1A2SLC1A1CA2MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040225006-A1 | (Hetero) bicyclymethanesulfonylamino-substituted hydroxamic acid derivates | SMITHKLINE BEECHAM P.L.C. | 2004-11-11 | — | — | US | disclosed |
| US-20030199571-A1 | (Hetero) Bicyclymethanesulfonylamino-substituted hydroxamic acid derivatives | SMITHKLINE BEECHAM P.L.C. (GB) | 2003-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030199571-A1 | (Hetero) Bicyclymethanesulfonylamino-substituted hydroxamic acid derivatives | CD40, CD22, CD2 | SLC1A3 403/4885SLC1A2 1833/4885SLC1A1 644/4885 |
| US-20040225006-A1 | (Hetero) bicyclymethanesulfonylamino-substituted hydroxamic acid derivates | CD40, TNFRSF1A, CD2 | SLC1A3 367/4885SLC1A2 1919/4885SLC1A1 562/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.