Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | ESR1 | P03372 | 2/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.52 |
| ▸ | TACR2 | P21452 | 2/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | SHBG | P04278 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.52 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL991821 | 1.00 | CYP3A4 (0.55) | CYP3A4TSHRESR1ADRA2AADORA3 | |
| SCHEMBL5885578 | 1.00 | CYP3A4 (0.55) | CYP3A4TSHRESR1ADRA2AADORA3 | |
| SCHEMBL2488182 | 1.00 | CYP3A4 (0.55) | CYP3A4TSHRESR1ADRA2AADORA3 | |
| SCHEMBL13725699 | 1.00 | CYP3A4 (0.55) | CYP3A4TSHRESR1ADRA2AADORA3 | |
| SCHEMBL5884680 | 1.00 | CYP3A4 (0.55) | CYP3A4TSHRESR1ADRA2AADORA3 | |
| SCHEMBL5885475 | 1.00 | CYP3A4 (0.55) | CYP3A4TSHRESR1ADRA2AADORA3 | |
| SCHEMBL5885366 | 1.00 | CYP3A4 (0.55) | CYP3A4TSHRESR1ADRA2AADORA3 | |
| SCHEMBL10400983 | 1.00 | CYP3A4 (0.55) | CYP3A4TSHRESR1ADRA2AADORA3 | |
| SCHEMBL1403683 | 0.98 | CYP3A4 (0.57) | CYP3A4TSHRESR1ADRA2AADORA3 | |
| SCHEMBL14565823 | 0.95 | CYP3A4 (0.65) | CYP3A4TSHRESR1ADRA2AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119285502-A | Free radical self-release antifouling agent containing oxime urethane group and preparation method and application thereof | 哈尔滨工程大学 | 2025-01-10 | — | — | CN | claimed |
| CN-119285502-A | Free radical self-release antifouling agent containing oxime urethane group and preparation method and application thereof | 哈尔滨工程大学 | 2025-01-10 | — | — | CN | disclosed |
| US-9962398-B2 | Sulfonamide compounds for inhibition of metastatic tumor growth | WELICHEM BIOTECH INC. (CA) | 2018-05-08 | — | — | US | disclosed |
| EP-2590938-B1 | NOVEL SULFONAMIDE COMPOUNDS FOR INHIBITION OF METASTATIC TUMOR GROWTH | WELICHEM BIOTECH INC (CA) | 2017-06-07 | — | — | EP | disclosed |
| US-20170007627-A1 | NOVEL SULFONAMIDE COMPOUNDS FOR INHIBITION OF METASTATIC TUMOR GROWTH | WELICHEM BIOTECH INC. (CA) | 2017-01-12 | — | — | US | disclosed |
| US-9463171-B2 | Sulfonamide compounds for inhibition of metastatic tumor growth | WELICHEM BIOTECH INC. (CA) | 2016-10-11 | — | — | US | disclosed |
| US-9029482-B2 | Method for preparing polycondensation resin | CHEIL INDUSTRIES INC. (KR) | 2015-05-12 | — | — | US | disclosed |
| US-8680282-B2 | Cyclic inhibitors of carnitine palmitoyltransferase and treating cancer | UNIVERSITY HEALTH NETWORK (CA) | 2014-03-25 | — | — | US | disclosed |
| US-20130190396-A1 | NOVEL SULFONAMIDE COMPOUNDS FOR INHIBITION OF METASTATIC TUMOR GROWTH | METASIGNAL THERAPEUTICS INC. (CA) | 2013-07-25 | — | — | US | disclosed |
| US-20130165621-A1 | Method for Preparing Polycondensation Resin | CHEIL INDUSTRIES INC. (KR) | 2013-06-27 | — | — | US | disclosed |
| US-7022257-B1 | Coating composition and floor material coated with said composition | SHIN-NAKAMURA CHEMICAL CO., LTD. (JP) | 2006-04-04 | — | — | US | disclosed |
| EP-1144395-B1 | 2-AMINO-BENZOXAZINONE DERIVATIVES FOR THE TREATMENT OF OBESITY | ALIZYME THERAPEUTICS LTD (GB) | 2005-04-20 | — | — | EP | disclosed |
| US-6656934-B2 | Enzyme inhibitor | ALIZYME THERAPEUTICS LIMITED (GB) | 2003-12-02 | — | — | US | disclosed |
| US-20030191123-A1 | 2-amino-benzoxazinone derivatives for the treatment of obesity | NORGINE B.V. (NL) | 2003-10-09 | — | — | US | disclosed |
| US-20030013707-A1 | 2-amino-benzoxazinone derivatives for the treatment of obesity | NORGINE B.V. (NL) | 2003-01-16 | — | — | US | disclosed |
| US-20020175299-A1 | Ultraviolet irradiation apparatus and method of forming cured coating film using the apparatus | GEN MAINTENANCE TECHNOLOGY INC. (JP) | 2002-11-28 | — | — | US | disclosed |
| CN-1354747-A | 2-amino-4H-3, 1-benzoxazin-4-one derivatives for the treatment of obesity | ALIZYME THERAPEUTICS LTD (GB) | 2002-06-19 | — | — | CN | disclosed |
| WO-2000040569-A9 | 2-AMINO-BENZOXAZINONE DERIVATIVES FOR THE TREATMENT OF OBESITY | ALIZYME THERAPEUTICS LTD (GB) | 2002-02-28 | — | — | WO | disclosed |
| EP-1143977-A1 | 2-OXY-BENZOXAZINONE DERIVATIVES FOR THE TREATMENT OF OBESITY | Alizyme Therapeutics Limited (GB) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000040247-A1 | 2-OXY-BENZOXAZINONE DERIVATIVES FOR THE TREATMENT OF OBESITY | ALIZYME THERAPEUTICS LIMITED (GB) | 2000-07-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130190396-A1 | NOVEL SULFONAMIDE COMPOUNDS FOR INHIBITION OF METASTATIC TUMOR GROWTH | HIF1AN, CBX2, HIF1A | CYP3A4 4648/4885TSHR 3691/4885ESR1 2795/4885 |
| US-20030191123-A1 | 2-amino-benzoxazinone derivatives for the treatment of obesity | CYP4X1, CYP2B6, BBOX1 | CYP3A4 64/4885TSHR 1571/4885ESR1 1982/4885 |
| US-20030013707-A1 | 2-amino-benzoxazinone derivatives for the treatment of obesity | CYP4X1, CYP2B6, BBOX1 | CYP3A4 64/4885TSHR 1571/4885ESR1 1982/4885 |
| US-20170007627-A1 | NOVEL SULFONAMIDE COMPOUNDS FOR INHIBITION OF METASTATIC TUMOR GROWTH | HIF1AN, CBX2, HIF1A | CYP3A4 4648/4885TSHR 3691/4885ESR1 2795/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.