SCHEMBL6734576

SCHEMBL6734576

CCOP(=O)(CC(O)CO)OCC

nearest known ligand 0.50

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 2/20 0.50
TSHR P16473 2/20 0.46
MAPT P10636 2/20 0.41
MAPK1 P28482 1/20 0.41
TP53 P04637 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
POLB P06746 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
UGT2B7 P16662 2/20 0.34
LMNA P02545 2/20 0.33
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15032899 0.89 TSHR (0.52) PPARDTSHRMAPTMAPK1TP53
SCHEMBL15317935 0.84 TSHR (0.48) PPARDTSHRMAPTMAPK1TP53
SCHEMBL13725745 0.81 GABRR1 (0.52) PPARDTSHRMAPTMAPK1TP53
SCHEMBL16132582 0.81 TSHR (0.44) PPARDTSHRMAPTMAPK1TP53
SCHEMBL10796826 0.81 TSHR (0.44) PPARDTSHRMAPTMAPK1TP53
SCHEMBL6734582 0.81 PPARD (0.52) PPARDTSHRTP53TDP1POLB
SCHEMBL18979175 0.80 PPARD (0.52) PPARDTSHRMAPTMAPK1TP53
SCHEMBL15011848 0.80 PPARD (0.52) PPARDTSHRMAPTMAPK1TP53
SCHEMBL3487454 0.79 PPARD (0.57) PPARDTSHRMAPTMAPK1TP53
SCHEMBL9343304 0.78 MAPT (0.45) PPARDTSHRMAPTMAPK1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180094007-A1 EPOXY PHOSPHONATE ESTER AS A COUPLING AGENT FOR TRANSITION METAL AND METAL OXIDE SURFACES THE CURATORS OF THE UNIVERSITY OF MISSOURI 2018-04-05 US disclosed
US-20180094007-A1 EPOXY PHOSPHONATE ESTER AS A COUPLING AGENT FOR TRANSITION METAL AND METAL OXIDE SURFACES THE CURATORS OF THE UNIVERSITY OF MISSOURI 2018-04-05 US disclosed
US-20180094007-A1 EPOXY PHOSPHONATE ESTER AS A COUPLING AGENT FOR TRANSITION METAL AND METAL OXIDE SURFACES THE CURATORS OF THE UNIVERSITY OF MISSOURI 2018-04-05 US disclosed
US-20170121354-A1 EPOXY PHOSPHONATE ESTER AS A COUPLING AGENT FOR TRANSITION METAL AND METAL OXIDE SURFACES US ARMY, SECRETARY OF THE ARMY 2017-05-04 US disclosed
US-20170121354-A1 EPOXY PHOSPHONATE ESTER AS A COUPLING AGENT FOR TRANSITION METAL AND METAL OXIDE SURFACES US ARMY, SECRETARY OF THE ARMY 2017-05-04 US disclosed
US-20170121354-A1 EPOXY PHOSPHONATE ESTER AS A COUPLING AGENT FOR TRANSITION METAL AND METAL OXIDE SURFACES US ARMY, SECRETARY OF THE ARMY 2017-05-04 US disclosed
US-20040010858-A1 Hydrophilically modified polyisocyanates and polyurethanes for crease-proofing textiles containing cellulose BASF AKTIENGESELLSCHAFT (DE) 2004-01-22 US disclosed
US-5776394-A Process for manufacturing cellulose fibres BASF AKTIENGESELLSCHAFT (DE) 1998-07-07 US disclosed
US-5470907-A Flow resistant polymers for finishes or coatings BASF AKTIENGESELLSCHAFT (DE) 1995-11-28 US disclosed
US-4861826-A Aqueous polyurethane adhesive dispersions BASF AKTIENGESELLSCHAFT (DE) 1989-08-29 US disclosed
US-4585703-A MELAMINE RESIN AND PHOSPHONATE FIREPROOFING AGENT DAINIPPON INK & CHEMICALS, INC. (JP) 1986-04-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180094007-A1 EPOXY PHOSPHONATE ESTER AS A COUPLING AGENT FOR TRANSITION METAL AND METAL OXIDE SURFACES PHOSPHO1, MSN, EPCAM PPARD 3580/4885TSHR 3857/4885MAPT 2387/4885
US-20170121354-A1 EPOXY PHOSPHONATE ESTER AS A COUPLING AGENT FOR TRANSITION METAL AND METAL OXIDE SURFACES PHOSPHO1, MSN, EPCAM PPARD 3580/4885TSHR 3857/4885MAPT 2387/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.