Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.38 |
| ▸ | STS | P08842 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CASP6 | P55212 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TYR | P14679 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL496727 | 0.75 | — | — | |
| SCHEMBL9035709 | 0.73 | NPSR1 (0.48) | ALDH1A1SMN1; SMN2LMNAMAPTHPGD | |
| SCHEMBL9050160 | 0.72 | — | — | |
| SCHEMBL9078760 | 0.72 | GAA (0.33) | ALDH1A1SMN1; SMN2POLBL3MBTL1 | |
| SCHEMBL8831007 | 0.71 | — | — | |
| SCHEMBL9049728 | 0.71 | — | — | |
| SCHEMBL1663469 | 0.69 | PARP10 (0.65) | ALDH1A1CYP2A6KDM4ESMN1; SMN2LMNA | |
| SCHEMBL5050902 | 0.69 | PARP10 (0.65) | ALDH1A1CYP2A6KDM4ESMN1; SMN2LMNA | |
| SCHEMBL13635189 | 0.68 | ALDH1A1 (0.41) | ALDH1A1CYP2A6KDM4ESMN1; SMN2LMNA | |
| Fluoromethane SCHEMBL28219755 | 0.67 | ALDH1A1 (0.62) | ALDH1A1CYP2A6KDM4ESMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0836591-A1 | SEMICARBAZONES HAVING CNS ACTIVITY AND PHARMACEUTICAL PREPARATIONS CONTAINING SAME | UNIVERSITY OF SASKATCHEWAN (CA) | 1998-04-22 | — | — | EP | claimed |
| WO-1996040628-A1 | SEMICARBAZONES HAVING CNS ACTIVITY AND PHARMACEUTICAL PREPARATIONS CONTAINING SAME | THE UNIVERSITY OF SASKATCHEWAN (CA) | 1996-12-19 | — | — | WO | claimed |
| US-RE38425-E1 | ANTICONVULSANTS ADMINISTERED ORALLLY | UNIVERSITY OF SASKATCHEWAN TECHNOLOGIES, INC. (CA) | 2004-02-10 | — | — | US | disclosed |
| EP-0836591-A1 | SEMICARBAZONES HAVING CNS ACTIVITY AND PHARMACEUTICAL PREPARATIONS CONTAINING SAME | UNIVERSITY OF SASKATCHEWAN (CA) | 1998-04-22 | — | — | EP | disclosed |
| US-5741818-A | ANTICONVULSANTS | UNIVERSITY OF SASKATCHEWAN (CA) | 1998-04-21 | — | — | US | disclosed |
| WO-1996040628-A1 | SEMICARBAZONES HAVING CNS ACTIVITY AND PHARMACEUTICAL PREPARATIONS CONTAINING SAME | THE UNIVERSITY OF SASKATCHEWAN (CA) | 1996-12-19 | — | — | WO | disclosed |