Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | PPID | Q08752 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7528187 | 1.00 | MAPT (0.62) | MAPTMEN1KMT2APPIDALDH1A1 | |
| SCHEMBL17845067 | 0.88 | MEN1 (0.53) | MAPTMEN1KMT2APPIDALDH1A1 | |
| SCHEMBL19602217 | 0.88 | MEN1 (0.53) | MAPTMEN1KMT2APPIDALDH1A1 | |
| SCHEMBL11720022 | 0.88 | MAPT (0.48) | MAPTMEN1KMT2APPIDALDH1A1 | |
| SCHEMBL11720041 | 0.88 | MAPT (0.48) | MAPTMEN1KMT2APPIDALDH1A1 | |
| SCHEMBL7697326 | 0.86 | ALDH1A1 (0.58) | MAPTMEN1KMT2AALDH1A1CYP2C9 | |
| SCHEMBL17320385 | 0.86 | ALDH1A1 (0.58) | MAPTMEN1KMT2AALDH1A1CYP2C9 | |
| SCHEMBL6590119 | 0.86 | ALDH1A1 (0.58) | MAPTMEN1KMT2AALDH1A1CYP2C9 | |
| SCHEMBL11726774 | 0.85 | MEN1 (0.50) | MAPTMEN1KMT2AALDH1A1CYP2C9 | |
| SCHEMBL11399159 | 0.85 | NAMPT (0.51) | MAPTKMT2APPIDALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040261198-A1 | Restructuring and finishing of keratin fibers | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 2004-12-30 | — | — | US | claimed |
| US-6281295-B1 | Enamines as vulcanization accelerators for natural or synthetic rubbers | GREAT LAKES CHEMICAL ITALIA S.R.L. (IT) | 2001-08-28 | — | — | US | disclosed |
| EP-0735083-B1 | Enamines as vulcanization accelerators for natural or synthetic rubbers | GREAT LAKES CHEMICAL EUROP (CH) | 2000-02-09 | — | — | EP | disclosed |
| EP-0735083-A1 | Enamines as vulcanization accelerators for natural or synthetic rubbers | GREAT LAKES CHEMICAL ITALIA S.r.l. (IT) | 1996-10-02 | — | — | EP | disclosed |
| US-4622332-A | Asymmetric diesters of Hantzsch dihydropyridines with hypotensive activity | BAYER AKTIENGESELLSCHAFT (DE) | 1986-11-11 | — | — | US | disclosed |
| US-4273573-A | Agents for regulating plant growth using 2-thiazolone-5-carboxylic acid compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1981-06-16 | — | — | US | disclosed |
| US-4027037-A | ARTHROPOD METAMORPHOSIS INHIBITORS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-05-31 | — | — | US | disclosed |
| US-3933834-A | CARDIOVASCULAR AGENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-01-20 | — | — | US | disclosed |
| US-3932436-A | 2-Thiazolone-5-carboxylic acid ester fungicidal agents | BAYER AKTIENGESELLSCHAFT (DT) | 1976-01-13 | — | — | US | disclosed |