SCHEMBL67350

SCHEMBL67350

CCCC(N)C(=O)OC(C)(C)C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS1 P29475 2/20 0.40
NOS3 P29474 1/20 0.40
NOS2 P35228 1/20 0.40
LTA4H P09960 1/20 0.39
SLC1A2 P43004 3/20 0.38
SLC1A1 P43005 3/20 0.38
GRIK1 P39086 3/20 0.38
GRIK2 Q13002 3/20 0.38
SLC1A3 P43003 2/20 0.38
CTSK P43235 5/20 0.37
CTSS P25774 2/20 0.37
DPP4 P27487 1/20 0.35
DPP8 Q6V1X1 1/20 0.35
DPP9 Q86TI2 1/20 0.35
DPP7 Q9UHL4 1/20 0.35
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
LMNA P02545 1/20 0.34
HSD17B10 Q99714 1/20 0.34
CHRM1 P11229 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5763676 1.00 NOS1 (0.40) NOS1NOS3NOS2LTA4HSLC1A2
SCHEMBL17449764 1.00 NOS1 (0.40) NOS1NOS3NOS2LTA4HSLC1A2
SCHEMBL67349 1.00 NOS1 (0.40) NOS1NOS3NOS2LTA4HSLC1A2
Hydrochloric Acid SCHEMBL311215 0.98 NOS1 (0.39) NOS1NOS3NOS2LTA4HSLC1A2
Bromide SCHEMBL8760868 0.98 NOS1 (0.39) NOS1NOS3NOS2LTA4HSLC1A2
Hydrochloric Acid SCHEMBL952472 0.98 NOS1 (0.39) NOS1NOS3NOS2LTA4HSLC1A2
SCHEMBL3294154 0.89 NOS1 (0.42) NOS1NOS3NOS2LTA4HSLC1A2
SCHEMBL5967210 0.88 SLC1A2 (0.46) NOS1NOS3NOS2SLC1A2SLC1A1
SCHEMBL7266730 0.88 SLC1A2 (0.46) NOS1NOS3NOS2SLC1A2SLC1A1
Hydrochloric Acid SCHEMBL5967206 0.86 SLC1A2 (0.44) NOS1LTA4HSLC1A2SLC1A1GRIK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118956991-B Synthesis method of chiral amine 天津凯莱英生物科技有限公司 2025-03-07 CN claimed
CN-118956991-A Synthesis method of chiral amine 天津凯莱英生物科技有限公司 2024-11-15 CN claimed
CN-122055354-A Lipid compounds and related compositions and uses 波西达治疗公司 2026-05-15 CN disclosed
CN-118956991-B Synthesis method of chiral amine 天津凯莱英生物科技有限公司 2025-03-07 CN disclosed
WO-2025049925-A2 LIPIDOID COMPOUNDS AND RELATED COMPOSITIONS AND USES POSEIDA THERAPEUTICS, INC. (US) 2025-03-06 WO disclosed
CN-118956991-A Synthesis method of chiral amine 天津凯莱英生物科技有限公司 2024-11-15 CN disclosed
EP-3530290-A1 ALPHA AMINOACID ESTER-DRUG CONJUGATES HYDROLYSABLE BY CARBOXYLESTERASE GlaxoSmithKline Intellectual Property Development Limited (GB) 2019-08-28 EP disclosed
US-10172846-B2 HCV NS-3 serine protease inhibitors MEDIVIR AB (SE) 2019-01-08 US disclosed
US-20170196849-A1 HCV NS-3 SERINE PROTEASE INHIBITORS MEDIVIR AB (SE) 2017-07-13 US disclosed
US-9328112-B2 Tetracyclic CDK9 kinase inhibitors ABBVIE INC. (US) 2016-05-03 US disclosed
CN-105392780-A Pathway specific assays for predicting irritable bowel syndrome diagnosis NESTEC SA 2016-03-09 CN disclosed
CN-101541800-A Pteridine derivatives as polo-like kinase inhibitors useful in the treatment of cancer CHROMA THERAPEUTICS LTD (GB) 2009-09-23 CN disclosed
US-20070203072-A1 Hcv Ns-3 Serine Protease Inhibitors MEDIVIR AB (SE) 2007-08-30 US disclosed
CN-1305846-C Urea derivatives SANTEN PHARCEUMATICAL CO LTD (JP) 2007-03-21 CN disclosed
EP-1040103-B1 ANILIDE DERIVATIVE, PRODUCTION AND USE THEREOF TAKEDA PHARMACEUTICAL (JP) 2007-03-14 EP disclosed
CN-1914225-A HCV NS-3 serine protease inhibitors MEDIVIR AB (SE) 2007-02-14 CN disclosed
EP-1713823-A2 HCV NS-3 SERINE PROTEASE INHIBITORS Medivir Aktiebolag (SE) 2006-10-25 EP disclosed
WO-2005073195-A2 HCV NS-3 SERINE PROTEASE INHIBITORS MEDIVIR AB (SE) 2005-08-11 WO disclosed
US-6268354-B1 Pharmaceutical composition for antagonizing CCR5 comprising anilide derivative TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2001-07-31 US disclosed
CN-1282326-A Anilide derivative, process for producing the same, and use thereof TAKEDA CHEMICAL INDUSTRIES LTD (JP) 2001-01-31 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170196849-A1 HCV NS-3 SERINE PROTEASE INHIBITORS HPN, CPN1, PRSS1 NOS1 3193/4885NOS3 1394/4885NOS2 3787/4885
US-20070203072-A1 Hcv Ns-3 Serine Protease Inhibitors HPN, CPN1, PRSS1 NOS1 2714/4885NOS3 1025/4885NOS2 3297/4885
US-10172846-B2 HCV NS-3 serine protease inhibitors HPN, CPN1, PRSS1 NOS1 3193/4885NOS3 1394/4885NOS2 3787/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.