SCHEMBL6735145

SCHEMBL6735145

CCOC(=O)C1CN(S(=O)(=O)c2ccc3cc(C(=N)N)ccc3c2)CCN1C(=O)c1nc2c(s1)CNC(C)C2

nearest known ligand 0.52

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
F10 P00742 14/20 0.52
F2 P00734 9/20 0.48
ALDH1A1 P00352 3/20 0.39
KMT2A Q03164 2/20 0.39
LMNA P02545 1/20 0.39
USP2 O75604 1/20 0.35
HSD17B10 Q99714 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6737044 0.98 F10 (0.50) F10F2ALDH1A1KMT2ALMNA
SCHEMBL6734068 0.92 F10 (0.51) F10F2ALDH1A1KMT2ALMNA
SCHEMBL6734071 0.92 F10 (0.51) F10F2ALDH1A1KMT2ALMNA
SCHEMBL6731851 0.91 F10 (0.47) F10F2ALDH1A1KMT2ALMNA
SCHEMBL6733726 0.90 F10 (0.56) F10F2
SCHEMBL6728355 0.90 F10 (0.49) F10F2ALDH1A1KMT2ALMNA
SCHEMBL6782188 0.90 F10 (0.49) F10F2ALDH1A1KMT2ALMNA
SCHEMBL6725182 0.90 F10 (0.47) F10F2ALDH1A1USP2HSD17B10
SCHEMBL6732353 0.89 F10 (0.40) F10F2ALDH1A1KMT2ALMNA
SCHEMBL6733144 0.89 F10 (0.40) F10F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040082611-A1 Anticoagulants; brain disorders; respiratory system disorders; side effect reduction DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2004-04-29 US disclosed
EP-1104754-A1 NOVEL SULFONYL DERIVATIVES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2001-06-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040082611-A1 Anticoagulants; brain disorders; respiratory system disorders; side effect reduction F2, CYC1, SULT2A1 F10 19/4885F2 1/4885ALDH1A1 1316/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.