SCHEMBL673556

SCHEMBL673556

CC1CN1C(=O)C(C)(C)C

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.44
MAPT P10636 1/20 0.44
GAA P10253 1/20 0.41
RIPK1 Q13546 3/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
PDK2 Q15119 3/20 0.37
PDK1 Q15118 2/20 0.37
PDK3 Q15120 2/20 0.37
PDK4 Q16654 2/20 0.37
LMNA P02545 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23133920 0.85 TSHR (0.39) TSHRMAPTGAARIPK1SMN1; SMN2
SCHEMBL23133916 0.85 TSHR (0.39) TSHRMAPTGAARIPK1SMN1; SMN2
SCHEMBL23134557 0.85 TSHR (0.39) TSHRMAPTGAARIPK1SMN1; SMN2
SCHEMBL23133932 0.85 TSHR (0.39) TSHRMAPTGAARIPK1SMN1; SMN2
SCHEMBL23133921 0.85 TSHR (0.39) TSHRMAPTGAARIPK1SMN1; SMN2
SCHEMBL23134615 0.85 TSHR (0.39) TSHRMAPTGAARIPK1SMN1; SMN2
SCHEMBL23133915 0.85 TSHR (0.39) TSHRMAPTGAARIPK1SMN1; SMN2
SCHEMBL18757310 0.84 RIPK1 (0.35) TSHRMAPTGAARIPK1SMN1; SMN2
SCHEMBL14165239 0.84 RIPK1 (0.35) TSHRMAPTGAARIPK1SMN1; SMN2
SCHEMBL25915051 0.84 TSHR (0.38) TSHRMAPTGAARIPK1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3456746-B1 TERMINAL-MODIFIED CONJUGATED DIENE-BASED POLYMER, RUBBER COMPOSITION, AND RUBBER ARTICLE BRIDGESTONE CORP (JP) 2023-04-19 EP disclosed
WO-2022124058-A1 POLYMER-METAL COMPLEX, TIRE, AND POLYMER ARTICLE 株式会社ブリヂストン 2022-06-16 WO disclosed
EP-3851489-A1 MODIFIED MULTI-COMPONENT COPOLYMER, RUBBER COMPOSITION, RESIN COMPOSITION, TIRE AND RESIN PRODUCT BRIDGESTONE CORPORATION (JP) 2021-07-21 EP disclosed
US-10875937-B2 Terminal-modified conjugated diene polymer, rubber composition and rubber article BRIDGESTONE CORPORATION (JP) 2020-12-29 US disclosed
CN-109071685-B Terminal-modified conjugated diene polymer, rubber composition, and rubber article 株式会社普利司通 2020-12-01 CN disclosed
WO-2020054484-A1 MODIFIED MULTI-COMPONENT COPOLYMER, RUBBER COMPOSITION, RESIN COMPOSITION, TIRE AND RESIN PRODUCT 株式会社ブリヂストン 2020-03-19 WO disclosed
CN-110325554-A Manufacturing method, modified conjugated diene polymer, rubber composition and the tire of modified conjugated diene polymer 株式会社普利司通 2019-10-11 CN disclosed
US-20190161571-A1 TERMINAL-MODIFIED CONJUGATED DIENE POLYMER, RUBBER COMPOSITION, RUBBER PRODUCT AND METHOD FOR MANUFACTURING TERMINAL-MODIFIED CONJUGATED DIENE POLYMER BRIDGESTONE CORPORATION (JP) 2019-05-30 US disclosed
EP-3466985-A1 TERMINALLY MODIFIED CONJUGATED DIENE POLYMER, RUBBER COMPOSITION, RUBBER PRODUCT, AND METHOD FOR PRODUCING TERMINALLY MODIFIED CONJUGATED DIENE POLYMER Bridgestone Corporation (JP) 2019-04-10 EP disclosed
EP-3456746-A1 TERMINAL-MODIFIED CONJUGATED DIENE-BASED POLYMER, RUBBER COMPOSITION, AND RUBBER ARTICLE Bridgestone Corporation (JP) 2019-03-20 EP disclosed
US-8202944-B2 excellent in low heat generating property, rupture characteristics and wear resistance comprising sulfur curable polybutadiene, polyisoprene, or copolymers with styrene, modified with aziridine compounds such as 1-butyrylaziridine, in the presence of initiators; improved dispersibility of carbon black BRIDGESTONE CORPORATION (JP) 2012-06-19 US disclosed
US-20110196086-A1 RUBBER COMPOSITION BRIDGESTONE CORPORATION (JP) 2011-08-11 US disclosed
US-7968652-B2 Modified conjugated diene copolymer, rubber compositions and tires BRIDGESTONE CORPORATION (JP) 2011-06-28 US disclosed
EP-2336233-A1 RUBBER COMPOSITION Bridgestone Corporation (JP) 2011-06-22 EP disclosed
US-20100160530-A1 RUBBER COMPOSITION CONTAINING MODIFIED POLYBUTADIENE RUBBER AND TIRE BRIDGESTRONE CORPORATION (JP) 2010-06-24 US disclosed
US-20090292043-A1 MODIFIED CONJUGATED DIENE COPOLYMER, RUBBER COMPOSITIONS AND TIRES BRIDGESTONE CORPORATION (JP) 2009-11-26 US disclosed
EP-1975200-A1 RUBBER COMPOSITION CONTAINING MODIFIED POLYBUTADIENE RUBBER AND TIRE Bridgestone Corporation (JP) 2008-10-01 EP disclosed
US-20080177017-A1 Modified Polymer, Rubber Composition, and Tire BRIDGESTONE CORPORATION (JP) 2008-07-24 US disclosed
EP-1873168-A1 MODIFIED CONJUGATED DIENE COPOLYMER, RUBBER COMPOSITIONS AND TIRES Bridgestone Corporation (JP) 2008-01-02 EP disclosed
EP-1834966-A1 MODIFIED POLYMER, RUBBER COMPOSITION, AND TIRE Bridgestone Corporation (JP) 2007-09-19 EP disclosed