Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | F2 | P00734 | 2/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 6/20 | 0.41 |
| ▸ | CA2 | P00918 | 6/20 | 0.41 |
| ▸ | CA5A | P35218 | 6/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6722992 | 0.93 | KMT2A (0.46) | KMT2AF2PRSS1PRSS2PRSS3 | |
| SCHEMBL6548726 | 0.92 | KMT2A (0.48) | KMT2AF2PRSS1PRSS2PRSS3 | |
| SCHEMBL6727898 | 0.91 | KMT2A (0.44) | KMT2AF2PRSS1PRSS2PRSS3 | |
| SCHEMBL6551184 | 0.91 | KMT2A (0.47) | KMT2AF2PRSS1PRSS2PRSS3 | |
| SCHEMBL6728649 | 0.90 | KMT2A (0.43) | KMT2AF2PRSS1PRSS2PRSS3 | |
| SCHEMBL6731251 | 0.90 | ALDH1A1 (0.49) | KMT2AF2PRSS1PRSS2PRSS3 | |
| SCHEMBL6734662 | 0.90 | KMT2A (0.48) | KMT2AF2PRSS1PRSS2PRSS3 | |
| SCHEMBL6723574 | 0.89 | KMT2A (0.43) | KMT2AF2PRSS1PRSS2PRSS3 | |
| SCHEMBL6727488 | 0.89 | F2 (0.47) | KMT2AF2PRSS1PRSS2PRSS3 | |
| SCHEMBL6731522 | 0.89 | SMN1; SMN2 (0.51) | KMT2AF2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040224251-A1 | Positive resist composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-11-11 | — | — | US | disclosed |
| US-6548220-B2 | Containing acid generator | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-04-15 | — | — | US | disclosed |