SCHEMBL6735829

SCHEMBL6735829

FC1=C(F)OC(c2ccccc2)(c2ccccc2)O1

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 7/20 0.38
MAOB P27338 7/20 0.34
MAOA P21397 4/20 0.34
CFTR P13569 1/20 0.34
GOPC Q9HD26 1/20 0.34
GAA P10253 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7442888 0.76 CNR1 (0.44) CNR1CFTRGOPCGAANPSR1
SCHEMBL30307890 0.76 CNR1 (0.44) CNR1CFTRGOPCGAANPSR1
SCHEMBL15337519 0.74 CNR1 (0.36) CNR1CFTRGOPCGAANPSR1
SCHEMBL1698175 0.71 CA1 (0.37) MAOBMAOACFTRGOPC
SCHEMBL9488195 0.71 OPRM1 (0.36) MAOBMAOACFTRGOPC
SCHEMBL4465770 0.71 CNR1 (0.40) CNR1
SCHEMBL13090171 0.69 CNR1 (0.50) CNR1NPSR1
SCHEMBL2828425 0.69 CNR1 (0.50) CNR1
SCHEMBL8122274 0.69 CFTR (0.39) CNR1CFTRGOPCGAANPSR1
SCHEMBL13655647 0.69 POLB (0.36) CNR1CFTRGOPCGAANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6682666-B2 ROTATING AND POLYMERIZING FIRST COMPONENT; FILLING LIQUID SECOND COMPONENT AND POLYMERIZING WHILE SUBJECTING FIRST COMPONENT TO DISSOLUTION, DIFFUSION OR RADIAL MIXING SAMSUNG ELECTRONICS CO., LTD. (KR) 2004-01-27 US claimed
US-20020031318-A1 Object with radially varying refractive index, and producing method and apparatus thereof SAMSUNG ELECTRONICS CO., LTD. (KR) 2002-03-14 US claimed
US-6682666-B2 ROTATING AND POLYMERIZING FIRST COMPONENT; FILLING LIQUID SECOND COMPONENT AND POLYMERIZING WHILE SUBJECTING FIRST COMPONENT TO DISSOLUTION, DIFFUSION OR RADIAL MIXING SAMSUNG ELECTRONICS CO., LTD. (KR) 2004-01-27 US disclosed
US-20020031318-A1 Object with radially varying refractive index, and producing method and apparatus thereof SAMSUNG ELECTRONICS CO., LTD. (KR) 2002-03-14 US disclosed