Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31337846 | 0.90 | ALDH1A1 (0.59) | ALDH1A1LMNAKMT2ATSHRMAPT | |
| SCHEMBL27288913 | 0.87 | ALDH1A1 (0.56) | ALDH1A1LMNAKMT2ATSHRMAPT | |
| SCHEMBL15256939 | 0.87 | ALDH1A1 (0.59) | ALDH1A1LMNAKMT2ATSHRMAPT | |
| SCHEMBL27782256 | 0.86 | ALDH1A1 (0.52) | ALDH1A1LMNAKMT2ATSHRMAPT | |
| SCHEMBL25249180 | 0.84 | ALDH1A1 (0.64) | ALDH1A1LMNAKMT2ATSHRMAPT | |
| SCHEMBL5935750 | 0.84 | ALDH1A1 (0.64) | ALDH1A1LMNAKMT2ATSHRMAPT | |
| SCHEMBL3506021 | 0.84 | ALDH1A1 (0.64) | ALDH1A1LMNAKMT2ATSHRMAPT | |
| SCHEMBL31571745 | 0.84 | ALDH1A1 (0.64) | ALDH1A1LMNAKMT2ATSHRMAPT | |
| SCHEMBL19810540 | 0.84 | ALDH1A1 (0.64) | ALDH1A1LMNAKMT2ATSHRMAPT | |
| SCHEMBL25291024 | 0.84 | ALDH1A1 (0.64) | ALDH1A1LMNAKMT2ATSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101941922-B | Liquid crystal compounds | ROLIC AG | 2012-02-29 | — | — | CN | disclosed |
| CN-101941922-A | Liquid crystalline cpd | ROLIC AG | 2011-01-12 | — | — | CN | disclosed |
| EP-1154981-B1 | LIQUID CRYSTAL COMPOUNDS | ROLIC AG (CH) | 2004-07-21 | — | — | EP | disclosed |
| US-6676851-B1 | LOW MELTING, GOOD ALIGNMENT ARYL BRANCHED ETHER-ESTER LINKED DIACRYLATES; REMAIN STABLE DURING COATING AND CROSSLINKING | ROLIC AG (CH) | 2004-01-13 | — | — | US | disclosed |
| CN-1340041-A | Liquid crystal compounds | ROLIC AG (CH) | 2002-03-13 | — | — | CN | disclosed |
| EP-1154981-A1 | LIQUID CRYSTAL COMPOUNDS | Rolic AG (CH) | 2001-11-21 | — | — | EP | disclosed |
| WO-2000048985-A1 | LIQUID CRYSTAL COMPOUNDS | ROLIC AG (CH) | 2000-08-24 | — | — | WO | disclosed |