SCHEMBL673657

SCHEMBL673657

CC1CN1C(=O)CC(=O)N1CC1C

nearest known ligand 0.58

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.58
TSHR P16473 3/20 0.52
MAPT P10636 1/20 0.46
GAA P10253 1/20 0.43
DPP4 P27487 1/20 0.33
ALDH1A1 P00352 2/20 0.32
LMNA P02545 1/20 0.32
NSD2 O96028 1/20 0.32
CHRNB2 P17787 3/20 0.32
CHRNA3 P32297 3/20 0.32
CHRNA4 P43681 3/20 0.32
CHRNB3 Q05901 2/20 0.32
CHRNA6 Q15825 2/20 0.32
NPC1 O15118 1/20 0.32
MDM2 Q00987 1/20 0.32
CHRNB4 P30926 1/20 0.31
CHRNA7 P36544 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL673795 0.83 SMN1; SMN2 (0.58) SMN1; SMN2TSHRMAPTGAAALDH1A1
SCHEMBL217915 0.81
SCHEMBL10938959 0.79 MAPT (0.60) SMN1; SMN2TSHRMAPTGAAALDH1A1
SCHEMBL11848165 0.79
SCHEMBL674365 0.79 SMN1; SMN2 (0.54) SMN1; SMN2TSHRMAPTGAANPC1
SCHEMBL673711 0.77
SCHEMBL1782094 0.77 SMN1; SMN2 (0.52) SMN1; SMN2TSHRMAPTGAANPC1
SCHEMBL10941068 0.75 SMN1; SMN2 (0.55) SMN1; SMN2TSHRMAPTGAACHRNB2
SCHEMBL672952 0.74 MEN1 (0.51) SMN1; SMN2TSHRMAPTALDH1A1CHRNB2
SCHEMBL7524022 0.73 TSHR (0.52) SMN1; SMN2TSHRMAPTGAALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3456746-B1 TERMINAL-MODIFIED CONJUGATED DIENE-BASED POLYMER, RUBBER COMPOSITION, AND RUBBER ARTICLE BRIDGESTONE CORP (JP) 2023-04-19 EP disclosed
WO-2022124058-A1 POLYMER-METAL COMPLEX, TIRE, AND POLYMER ARTICLE 株式会社ブリヂストン 2022-06-16 WO disclosed
EP-3851489-A1 MODIFIED MULTI-COMPONENT COPOLYMER, RUBBER COMPOSITION, RESIN COMPOSITION, TIRE AND RESIN PRODUCT BRIDGESTONE CORPORATION (JP) 2021-07-21 EP disclosed
US-10875937-B2 Terminal-modified conjugated diene polymer, rubber composition and rubber article BRIDGESTONE CORPORATION (JP) 2020-12-29 US disclosed
CN-109071685-B Terminal-modified conjugated diene polymer, rubber composition, and rubber article 株式会社普利司通 2020-12-01 CN disclosed
US-20190161571-A1 TERMINAL-MODIFIED CONJUGATED DIENE POLYMER, RUBBER COMPOSITION, RUBBER PRODUCT AND METHOD FOR MANUFACTURING TERMINAL-MODIFIED CONJUGATED DIENE POLYMER BRIDGESTONE CORPORATION (JP) 2019-05-30 US disclosed
US-20190153123-A1 TERMINAL-MODIFIED CONJUGATED DIENE POLYMER, RUBBER COMPOSITION AND RUBBER ARTICLE BRIDGESTONE CORPORATION (JP) 2019-05-23 US disclosed
EP-3466985-A1 TERMINALLY MODIFIED CONJUGATED DIENE POLYMER, RUBBER COMPOSITION, RUBBER PRODUCT, AND METHOD FOR PRODUCING TERMINALLY MODIFIED CONJUGATED DIENE POLYMER Bridgestone Corporation (JP) 2019-04-10 EP disclosed
EP-3456746-A1 TERMINAL-MODIFIED CONJUGATED DIENE-BASED POLYMER, RUBBER COMPOSITION, AND RUBBER ARTICLE Bridgestone Corporation (JP) 2019-03-20 EP disclosed
US-10131722-B2 Method for preparing terminal-modified conjugated diene polymer, terminal-modified conjugated diene polymer, rubber composition and tire BRIDGESTONE CORPORATION (JP) 2018-11-20 US disclosed
US-8309657-B2 Rubber composition BRIDGESTONE CORPORATION (JP) 2012-11-13 US disclosed
US-8202944-B2 excellent in low heat generating property, rupture characteristics and wear resistance comprising sulfur curable polybutadiene, polyisoprene, or copolymers with styrene, modified with aziridine compounds such as 1-butyrylaziridine, in the presence of initiators; improved dispersibility of carbon black BRIDGESTONE CORPORATION (JP) 2012-06-19 US disclosed
US-7968652-B2 Modified conjugated diene copolymer, rubber compositions and tires BRIDGESTONE CORPORATION (JP) 2011-06-28 US disclosed
EP-2336233-A1 RUBBER COMPOSITION Bridgestone Corporation (JP) 2011-06-22 EP disclosed
US-20100160530-A1 RUBBER COMPOSITION CONTAINING MODIFIED POLYBUTADIENE RUBBER AND TIRE BRIDGESTRONE CORPORATION (JP) 2010-06-24 US disclosed
US-20090292043-A1 MODIFIED CONJUGATED DIENE COPOLYMER, RUBBER COMPOSITIONS AND TIRES BRIDGESTONE CORPORATION (JP) 2009-11-26 US disclosed
EP-1975200-A1 RUBBER COMPOSITION CONTAINING MODIFIED POLYBUTADIENE RUBBER AND TIRE Bridgestone Corporation (JP) 2008-10-01 EP disclosed
US-20080177017-A1 Modified Polymer, Rubber Composition, and Tire BRIDGESTONE CORPORATION (JP) 2008-07-24 US disclosed
EP-1873168-A1 MODIFIED CONJUGATED DIENE COPOLYMER, RUBBER COMPOSITIONS AND TIRES Bridgestone Corporation (JP) 2008-01-02 EP disclosed
EP-1834966-A1 MODIFIED POLYMER, RUBBER COMPOSITION, AND TIRE Bridgestone Corporation (JP) 2007-09-19 EP disclosed